Bmi Korea Co., Ltd

Catholic University Industry Academic Cooperation Foundation

Yeong-Jun Baik

Sung-Hee Lee

Koo Woo

Choun-Ki Joo

Jun-Sub Choi

Ha-Na Kim

This invention relates to a stable hyaluronidase liquid formulation comprising a hyaluronidase and a stabilizer for hyaluronidase. In particular, the hyaluronidase has a purity of 95% or more and the specific activity of 70,000 IU/mg or more, and the stabilizer for hyaluronidase contains a buffering agent in order to provide pH of 4.0 to 6.0; 0.001 to 0.5 v/v % of a non-ionic surfactant; and 0.1 to 5 mM of a chelating agent or MgCl. The liquid formulation has advantages in that it stably maintains its activity for a long period of time and may be easily administered than the conventional formulations.

Stabilizer for hyaluronidase and liquid formulation comprising hyaluronidase

The present invention relates to a composition for inhibiting after-cataract including a hydrophilic sulfasalazine; a high content of hyaluronic acid; and a carrier containing an aqueous solution, and a method of preparing a composition for inhibiting after-cataract including the steps of adding hyaluronic acid powder to a hydrophilized sulfasalazine; and mixing the same with a specific condition.

Composition for inhibiting after-cataract and method of preparing the same

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Seoul, South Korea

Yeong-Jun Baik