Glyconex, Inc.

Yen-Ying Chen

Yu-Yu Lin

Tong-Hsuan Chang

Shu-Yen Chang

Jerry Ting

Mei-Chun Yang

Shu-Lun Tang

Liahng-Yirn Liu

Liahng-Yim Liu

Disclosed herein are humanized antibodies, antigen-binding fragments thereof, and antibody conjugates, that are capable of specifically binding to certain biantennary Lewis antigens, which antigens are expressed in a variety of cancers. The presently disclosed antibodies are useful to target antigen-expressing cells for treatment or detection of disease, including various cancers. Also provided are polynucleotides, vectors, and host cells for producing the disclosed antibodies and antigen-binding fragments thereof. Pharmaceutical compositions, methods of treatment and detection, and uses of the antibodies, antigen-binding fragments, antibody conjugates, and compositions are also provided.

Therapeutic antibodies

Growing community of inventors

Taipei, Taiwan

Yen-Ying Chen