Grape King Bio Ltd

Yen-Po Chen

Chin-Chu Chen

Yen-Lien Chen

Yang-Tzu Shih

Ching-Wen Lin

Jia-Lin Jiang

Yu-Hsin Hou

Ci-Sian Wang

Ya-Jyun Chen

Shih-Wei Lin

Szu-Yin Wu

Shin-Wei Lin

Hsiao-Ling Chang

You-Shan Tsai

Zi-He Wu

Hsing-Chun Kuo

The present disclosure relates to as external composition for wound healing containing afermentation product, which comprises afermentation product as an effective component. Thefermentation product is a bacteria-free concentrated filtrate from fermentation ofand the effective component is loaded onto a pharmaceutically acceptable absorbent carrier or carrying agent. The external composition for wound healing has anti-inflammatory and healing promoting effects on a skin wound after applied directly onto the skin wound.

External composition for wound healing containing lactobacillus fermentation product and method for promoting wound healing using the same

The present invention provides an active substance of, its use and a composition thereof for improving disturbance of reproductive function, especially, for manufacturing a pharmaceutical composition to improve disturbance of reproductive function induced by obesity or metabolic syndrome. The composition with the active substance ofcan effectively improve the structural integrity of testicular tissues and sperm, increase testosterone levels in the blood, and reduce the oxidation stress in sperms.

Active substance of, its use and a composition thereof for improving the reproductive function

The present invention provides aGKK2, a composition comprising thereof and its use for improving asthma, especially for lowering airway resistance, reducing levels of non-specific and specific IgE in serum, alleviating bronchoconstriction and increasing levels of GSH reductase in liver tissue interstitial fluid to improve allergic asthma.

Bifidobacterium lactis GKK2, a composition comprising thereof and its use for improving allergic asthma

The present invention provides aGKF3, a composition comprising the strain and their use, in which the aforementionedGKF3, deposited with accession numbers of BCRC 910824 and CGMCC 15203, can increase the levels of dopamine or/and serotonin in brain tissues, thereby improving the symptoms of the psychataxia such as decreased focus.

GKF3, composition comprising the strain and method for improving psychataxia using the same

The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.

Active substance ofGKS6, a composition comprising thereof and its use for promoting longevity

The present invention discloses uses of treating, preventing or improving bone diseases byor a composition including the. Theand compositions can increase the blood calcium concentration, the trabecular bone volume density, the trabecular thickness, the trabecular number and the bone mineral density of a subject, and reduce trabecular spacing of the subject. Further, the present invention discloses a method for treating a subject diagnosed with a bone disease, through identifying the subject having the bone disease and administering to the subject an effective amount of a composition including at least one ofGKM3 andGKS6, wherein theGKM3 is deposited in China General Microbiological Culture Collection Center (CGMCC) with a deposition number of CGMCC 14565 on Aug. 25, 2017, and theGKS6 is deposited in CGMCC with a deposition number of CGMCC 14566 on Aug. 25, 2017.

Method and composition for preventing, treating or relieving bone diseases

The present invention provides ahaving active substances, a composition comprising the same, and a method of promoting longevity using the same by subjecting the composition to a subject, thereby increasing Cisd2 gene expression, reducing damage of mitochondria, delaying aging-related symptoms including nerve degeneration and sarcopenia, and so on.

Growing community of inventors

Taoyuan, Taiwan

Yen-Po Chen