Grape King Bio Ltd

Grape King Inc.

Yen-Lien Chen

Chin-Chu Chen

Yen-Po Chen

Yang-Tzu Shih

Ching-Wen Lin

Jia-Lin Jiang

Yu-Hsin Hou

Ci-Sian Wang

Ya-Jyun Chen

Shih-Wei Lin

Shin-Wei Lin

Li-Ya Lee

Jui-Hsia Hsu

Szu-Yin Wu

Shu-Hsing Yeh

Pei-Cheng Lin

Han-Hsin Chang

Lee-Sar Sheng

Ying-Shih Feng

Charng-Cherng Chyau

Ching-Nung Chen

Shih-Jeng Huang

Hung-Ping Tseng

Wei-Hui Chung

Yi-Hsuan Chen

You-Shan Tsai

Zi-He Wu

Hsing-Chun Kuo

The present disclosure relates to as external composition for wound healing containing afermentation product, which comprises afermentation product as an effective component. Thefermentation product is a bacteria-free concentrated filtrate from fermentation ofand the effective component is loaded onto a pharmaceutically acceptable absorbent carrier or carrying agent. The external composition for wound healing has anti-inflammatory and healing promoting effects on a skin wound after applied directly onto the skin wound.

External composition for wound healing containing lactobacillus fermentation product and method for promoting wound healing using the same

The present invention provides aGKK2, a composition comprising thereof and its use for improving asthma, especially for lowering airway resistance, reducing levels of non-specific and specific IgE in serum, alleviating bronchoconstriction and increasing levels of GSH reductase in liver tissue interstitial fluid to improve allergic asthma.

Bifidobacterium lactis GKK2, a composition comprising thereof and its use for improving allergic asthma

The present invention provides aGKF3, a composition comprising the strain and their use, in which the aforementionedGKF3, deposited with accession numbers of BCRC 910824 and CGMCC 15203, can increase the levels of dopamine or/and serotonin in brain tissues, thereby improving the symptoms of the psychataxia such as decreased focus.

GKF3, composition comprising the strain and method for improving psychataxia using the same

The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.

Active substance ofGKS6, a composition comprising thereof and its use for promoting longevity

The present invention discloses uses of treating, preventing or improving bone diseases byor a composition including the. Theand compositions can increase the blood calcium concentration, the trabecular bone volume density, the trabecular thickness, the trabecular number and the bone mineral density of a subject, and reduce trabecular spacing of the subject. Further, the present invention discloses a method for treating a subject diagnosed with a bone disease, through identifying the subject having the bone disease and administering to the subject an effective amount of a composition including at least one ofGKM3 andGKS6, wherein theGKM3 is deposited in China General Microbiological Culture Collection Center (CGMCC) with a deposition number of CGMCC 14565 on Aug. 25, 2017, and theGKS6 is deposited in CGMCC with a deposition number of CGMCC 14566 on Aug. 25, 2017.

Method and composition for preventing, treating or relieving bone diseases

The present invention provides ahaving active substances, a composition comprising the same, and a method of promoting longevity using the same by subjecting the composition to a subject, thereby increasing Cisd2 gene expression, reducing damage of mitochondria, delaying aging-related symptoms including nerve degeneration and sarcopenia, and so on.

Active substances ofGKK2, composition comprising the same and method of promoting longevity using the same

The present invention discloses themycelia, the active substances ofmycelia, its submerged fermentation product and its pharmaceutical composition for preventing, delaying or treating cataracts, and the methods for preparing the products above. Themycelia, the active substances ofmycelia, its submerged fermentation product and its pharmaceutical composition further can be prepared as a health food for preventing or delaying cataracts.

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The present invention provides a method for producing a novel &#x3b2;-lactam antibiotic from a protoplast fusion strain. The method is to fermentatively culture the protoplast fusion strain ofand. The ferment filtrate is isolated, lyophilized, and extracted by acetone or acetone/methanol. The extract is concentrated by decompression, and then analyzed by preparation type HPLC to isolate the active antibiotic compound.

Method for producing novel &#x3b2;-lactam antibiotic from protoplast fusion strain

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Taoyuan, Taiwan

Yen-Lien Chen