National Health Research Institutes

Yen-Chun Lee

Jyh-Haur Chern

Chung-Chi Lee

Yu-Sheng Chao

Tsu-An Hsu

Shin-Ru Shih

Li-Wen Wang

Chih-Shiang Chang

Iou-Jiun Kang

Chiung-Tong Chen

Chia-Liang Tai

Yen-Shian Wu

Sheng-Ju Hsu

Yueh Andrew Yueh

A compound of the following formula: in which R, R, R, U, V, T, W, X, Y, Z, m, n, p, x, y, and z are as defined herein. Also disclosed are (1) a pharmaceutical composition containing such a compound, and (2) a method for treating Hepatitis C virus infection using such a compound.

Hepatitis C virus inhibitors

Imidazolidinone and imidazolinethione compounds of formula (I): wherein R, R, R, A, A, X, Y, Z, m, n, p, x, and y are defined herein. Also disclosed is a method of treating hepatitis C virus infection with these compounds.

Imidazolidinone and imidazolidinethione derivatives

Thiourea compounds of the following formula: wherein n, R, R, R, A, A, X, Y, and Z are defined herein. Also disclosed is a method of treating hepatitis C virus infection with these compounds.

Thiourea derivatives

This invention relates to compounds of the following formula: in which R, R, A, A, X, Y, m, n, p, x and y are as defined herein, pharmaceutical compositions comprising the compounds and use of the compounds in treating enterovirus infection.

Imidazolidinone compounds

Compounds of the following formula: in which R, R, A, A, X, Y, m, n, p, x and y are as defined herein. Also disclosed are pharmaceutical compositions each containing one or more of these compounds, and use thereof in treating enteroviral infection.

Growing community of inventors

Taitung, Taiwan

Yen-Chun Lee