Skhynix Inc.

Korea Institute of Science and Technology

Seoul National University

Yejin Lee

Jin Woo Park

Jae Wook Lee

Tae Jun Ham

Jun Heo

Oh-Seung Kwon

Jaeyoung Jang

Jaeyeon Won

Junghyun Son

Yoeseph Cho

Hana Park

Seongeun Jeon

Disclosed is a method for simultaneous analysis of neurotransmitters and/or their metabolites. The method includes (a) separating analytes including a plurality of neurotransmitters and/or their metabolites from a sample selected from body tissues, body fluids, secretions, and excretions, (b) derivatizing the analytes with ethyl chloroformate to obtain derivatives of the plurality of neurotransmitters and/or their metabolites, (c) separating the derivatives of the plurality of neurotransmitters and/or their metabolites by liquid chromatography, and (d) subjecting the separated derivatives of the neurotransmitters or their metabolites to multiple reaction monitoring (MRM) using a mass spectrometer. According to the method, a plurality of neurotransmitters in a very small amount of sample can be simultaneously analyzed in an accurate and rapid manner based on derivatization to increase the stability and ionization efficiency of the substances.

Method for simultaneous analysis of neurotransmitters and their metabolites based on derivatization

A hardware accelerator includes a block processing circuit configured to read a block from a list stored in an inverted index structure; and a search core configured to extract a document number out of a read block read by the block processing circuit and to calculate a score corresponding to the document number.

Hardware accelerator performing search using inverted index structure and search system including the hardware accelerator

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Seoul, South Korea

Yejin Lee