Nanyang Technological University

Yehai Yan

Bee Eng Mary Chan

Qing Zhang

Longqing Chen

Bin He

Aiping Zhu

Chee Yoon Yue

Jinye Shen

Sai Li

In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular grafts, for example. In one embodiment, an ultraviolet (UV) resin made from a diacrylated biodegradable oligomer is molded into a flexible scaffold having cavities and/or channels. Channel/cavity size may be on the order of micrometers and/or nanometers, and thus the walls may have high aspect ratios. Smooth muscle cells may be deposited in the channels and because of the high aspect ratios, the cells may align along the channels/cavities as confluence is reached.

Micro-structured and nano-structured surfaces on biodegradable polymers

A method of aligning nanotubes is described, where a plurality of channels is provided on a substrate (), a suspension of nanotubes is placed on or adjacent an open surface of the channels () and the suspension is allowed to flow into the channels to align the nanotubes substantially parallel to the longitudinal axis of the channels ().

Method of aligning nanotubes

Growing community of inventors

Singapore, Singapore

Yehai Yan