Pennwalt Corporation

Fisons Ltd.

Yegnaswami Raghunathan

San-Laung Chow

Coatings for individual ion exchange resin particles comprised of (a) ethylcellulose and (b) corn oil or acetylated monoglycerides.

Coating barriers comprising ethyl cellulose

Sulfonic acid cationic exchange resin particles which have been treated to improve their coatability with up to about 20% by weight of a compound selected from hydroxypropylmethyl cellulose, hydroxypropyl cellulose, hydroxypropyl sorbitol, sorbitol, and polyvinylpyrrolidone.

Coatable ion exchange resins

Sulfonic acid cationic exchange resin particles which have been treated to improve their coatability with minor amounts of high molecular weight polymers selected from carboxypolymethylene, xanthan gum, and propylene glycol alginate.

Polymer-treated ion exchange resins

Controlled release pharmaceutical preparations containing coated sulfonic acid cationic exchange resin drug complex particles, the resin particles having been treated, prior to coating, with about 15 to 25% by weight of glycerin, based on the combined weight of the glycerin and the drug resin complex particles.

Controlled release pharmaceutical preparations

A combination tablet containing metolazone and triamterene is useful in diuretic therapy and the treatment of hypertension. The composition is advantageous in the prevention of hypokalemia, a common side effect of diuretic therapy and possesses enhanced dissolution properties. Proper selection of the excipient formulation permits preparation of the tablets by direct compression.

Diuretic/antihypertensive compositions

Prolonged release pharmaceutical preparations containing ion exchange resin drug complexes at least a substantial portion of which have been treated with a solvating agent and provided with a diffusion barrier coating.

Growing community of inventors

Perinton, NY, United States of America

Yegnaswami Raghunathan