Sumika Fine Chemicals, Co.,ltd.

Yayoi Tagami

Nobushige Itaya

Tadashi Katsura

Masami Igi

Kiyoshi Sugi

Yoshihiro Kawada

Shigeya Yamazaki

Taro Ishibashi

Teiji Yamaoka

Process for preparing a piperidine derivative

Piperidine derivative and process for preparing the same

A piperidine derivative, which can be used as an intermediate for pharmaceuticals such as paroxetine useful as antidepressants, represented by the general formula (I): ##STR1## wherein R.sup.1 is hydrogen atom, benzyloxycarbonyl group or tert-butoxycarbonyl group; R.sup.2 is hydroxymethyl group, an alkylsulfonyloxymethyl group having an alkyl moiety of 1 to 2 carbon atoms, phenylsulfonyloxymethyl group which may have methyl group at the 4-position, (3,4-methylenedioxyphenyl)oxymethyl group, carboxyl group or --CO.sub.2 R.sup.7 group in which R.sup.7 is an alkyl group having 1 to 5 carbon atoms, and Z is methylene group or carbonyl group.

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Osaka, Japan

Yayoi Tagami