Novartis Ag

Novartis Pharma Gmbh

Yatindra Joshi

Moise Azria

Ping Li

Ashish B Patel

Alan Edward Royce

Robert Frank Wagner

Madhusudhan Pudipeddi

Jiahao Zhu

Linda Mindeholm

Rosario Lobrutto

Yu Cao

James Kowalski

Jay Parthiban Lakshman

Wei-Qin Tong

Madhav Vasanthavada

Ashish Bipin Patel

Monolayer, bilayer and trilayer solid dosage forms of a combination of valsartan, amlodipine and hydrochlorothiazide are made.

Solid dosage forms of valsartan, amlodipine and hydrochlorothiazide and method of making the same

The invention is directed to a method of administering pharmaceutical compositions comprising peptide drugs such as a calcitonin in combination with one or more oral delivery agents, together with an amount of a liquid, and method of treatment of disorders responsive to the action of peptide drugs such as a calcitonin employing such method of administration so as to enhance the oral bioavailability of a calcitonin. The methods of the invention increase the oral absorption and systemic bioavailability of peptide drugs, such as a calcitonin.

Oral administration of a calcitonin

The present invention relates to dosage forms of human growth hormone, the use of an absorption enhancer to allow absorption of human growth hormone into the systemic circulation in a biologically active form, in particular after oral administration, as well as the use of oral dosage forms comprising human growth hormone and an absorption enhancer for the treatment of human growth hormone deficiencies and disorders associated therewith.

Pharmaceutical compositions comprising hGH for oral delivery

Growing community of inventors

Princeton, NJ, United States of America

Yatindra Joshi