Kyowa Hakko Kogyo Co., Ltd.

Yasuyuki Ono

Masaji Kasai

Yukiteru Mimura

Shinji Tomioka

Yoshiyuki Yamada

Kazumi Amatsu

Shoichi Mizutaki

Yutaka Osawa

Kunimi Inoue

Hiroyuki Shinmura

Yasunori Nakaguchi

Disclosed is a process for producing alanylglutamine, which comprises reacting an N-(2-substituted)-propionylglutamine compound represented by the formula (I): ##STR1## where X represents halogen, alkylsulfonyloxy, or substituted or unsubstituted arylsulfonyloxy, with ammonia at a temperature of 60.degree. C. or below. in accordance with the present invention, highly purified alanylglutamine can be produced in a high yield, without racemization.

Process for producing alanylglutamine

Disclosed is a process for producing alanylglutamine, which comprises reacting an N-(2-substituted)-propionylglutamine compound represented by the formula (I): ##STR1## where X represents halogen, alkylsulfonyloxy, or substituted or unsubstituted arylsulfonyloxy, with ammonia at a temperature of 60.degree. C. or below. In accordance with the present invention, highly purified alanylglutamine can be produced in a high yield, without racemization.

Process for producing alanylgutamine

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Isehara, Japan

Yasuyuki Ono