Takeda Chemical Industries, Inc.

Sumitomo Chemical Takeda Agro Company, Limited

Yasuyuki Kando

Isao Minamida

Hideki Uneme

Toshiyuki Kiji

Tetsuo Okauchi

Kazuho Matsuura

Hitoshi Ishizuka

Junji Yamada

Toshiya Kamikado

Atsuo Akayama

Makota Noguchi

Makoto Noguchi

Shinichi Masada

Akayama Atsuo

Processes for production of oxadiazoline derivatives

Arylpyrazole insecticides

The present invention relates to a compound of the formula &lsqb;I&rsqb;:

Oxadiazoline derivative and their use as insecticides

Novel Intermediates ##STR1## wherein R is a substituted or unsubstituted hydrocarbon residue or acyl group; X is an electron withdrawing group; Y.sup.1 and Y.sup.2, which are the same or different, are each independently oxygen or sulfur; and A is a substituted or unsubstituted, divalent hydrocarbon residue have potent reactivity, this being useful in preparing guanidine derivatives.

Synthetic Intermediates for the preparation of N, N'-Di-substituted

##STR1## wherein R is a substituted or unsubstituted hydrocarbon residue or acyl group; X is an electron withdrawing group; Y.sup.1 and Y.sup.2, which are the same or different, are each independently oxygen or sulfur; and A is a substituted or unsubstituted, divalent hydrocarbon residue have potent reactivity, this being useful in preparing guanidine derivatives.

Process for preparing and using guanidine derivatives

Novel substituted nitroguanidine derivatives and salts thereof having the following formula: ##STR1## wherein R.sup.1 is a substituted or unsubstituted heterocyclic group; R.sup.2 is a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, --CO--OR.sup.6 wherein R.sup.6 is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or --CO--NR.sup.7 R.sup.8 wherein R.sup.7 and R.sup.8, which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R.sup.7 and R.sup.8, taken together with the nitrogen atom to which they are attached are a cyclic amino group; R.sup.3 is hydrogen, a substituted or unsubstituted hydrocarbon group (except for one substituted with an oxo group at the binding site), a group attached through a sulfur atom, a group attached through a phosphorus atom, cyano, --CO--R.sup.9 wherein R.sup.9 is hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, --CO--OR.sup.10 wherein R.sup.10 is a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or --CO--NR.sup.11 R.sup.12 wherein R.sup.11 and R.sup.12, which are the same or different, are each independently hydrogen, a substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted heterocyclic group, or R.sup.11 and R.sup.12, taken together with the nitrogen atom to which they are attached are a cyclic amino group; and R.sup.4 is hydrogen or a lower alkyl group; which have unexpectedly potent pesticidal activity and very low toxicity.

Substituted guanidine derivatives, their preparation and use

This invention relates to a compound of the formula: ##STR1## wherein R.sup.1 is hydrogen, a halogen or a lower alkyl group; R.sup.2 and R.sup.33 independently are a lower alkoxyl group; and Py is an optionally substituted pyridyl group or a salt thereof. The compound or a salt thereof exerts excellent fungicidal effects against plant disease and is used as fungicide for agricultural use.

Acrylic acid morpholides and fungicidal compositions

Growing community of inventors

Tsukuba, Japan

Yasuyuki Kando