Eisai Company, Limited

Other

Yasuyuki Asai

Kazuhide Ashizawa

Sumio Watanabe

Yasuo Kuwabara

Masanori Matsukawa

Yasuo Ishibashi

Kazuhiro Kaneko

Tomohiro Watanabe

Kiyoshi Iwamoto

Masahiro Mizuno

Katsumi Onai

Ikuo Kushida

Kiyomi Kikuchi

Yoshihisa Sano

Katsuhiro Kajio

Yixin Zeng

The present invention provides an evaluation method and preparation process of injection containing a lipid A analog. Specifically, it provides, in an injection preparation containing a lipid A analog or a pharmacologically acceptable salt thereof, forecasting and evaluating methods of the pharmacokinetics of the lipid A analog, and quality evaluating method and preparation process of the injection, which each comprises measuring membrane fluidity and/or circular dichroism.

Method for evaluating lipid a analog-containing injections

A fuel cell has a plurality of unit cells each including electrodes sandwiching an electrolyte membrane in-between, and a plurality of separators ( ) each arranged between the unit cells. Each separator ( ) has a plurality of contact lugs ( ) facing the electrodes and contacting the electrodes at pre-set contact widths and a plurality of fluid ducts ( ) each having a space between neighboring ones of the contact lugs ( ) as a duct width. The contact width of the contact lugs ( ) on a side closer to a fluid outlet is set smaller than that of the contact lugs ( ) on a side closer to a fluid inlet. Diffusion of an active material in an active material containing fluid into the inside of electrodes on a downstream side of a fluid duct, that is on a side closer to a fluid outlet, is facilitated.

Fuel cell and separator comprising contact lugs with specific widths

The present invention provides a preparation for injection containing a lipid A analog and a process for preparing the same. A preparation for injection prepared by dissolving a lipid A analog or a pharmacologically acceptable salt thereof in an alkaline aqueous solution, at an elevated temperature if necessary, and then adding a buffer thereto, and a process for preparing the same.

Injections containing lipid a analogues and process for the preparation thereof

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Aichi, Japan

Yasuyuki Asai