Other

National Hospital Organization Kinki-Chuo Chest Medical Center

Azbio Corporation

National Hospital Organization

Okada, Masaji

Takamori, Yasushi

Yasushi Takamori

Kazuyuki Ogawa

Kinya Nagata

Masaji Okada

(Problems) To provide a therapeutic agent for infections comprising granulysin as an active ingredient which has little side effect and no cytotoxicity and to which bacteria can hardly acquire resistance, and a treatment method using the same. (Means for Solving Problems) The present invention provides a therapeutic agent for infections comprising as active ingredient: 15K granulysin, a combination of 15K granulysin and 15K granulysin in vivo expression vector, a combination of 15K granulysin and at least one interleukin selected from IL-6, IL-23 or IL-27, a combination of 15K granulysin in vivo expression vector and at least one interleukin selected from IL-6, IL-23 or IL-27, or a combination of 15K granulysin in vivo expression vector and HSP65DNA and IL-12DNA in vivo expression vector, which enhances killing effects on bacteria and has less side effect, and to which bacteria can hardly acquire resistance, and a treatment method using the same.

Therapeutic agent for infections, and treatment method using same

Therapeutic agent for infections, and treatment method using the same

Growing community of inventors

Tokyo, Japan

Yasushi Takamori