Kabushiki Kaisha Toshiba

Pola Pharma Inc.

Yasushi Murakami

Nobuo Kubota

Azuma Nishio

Naoko Kobayashi

Hiroki Shoki

Hidehiro Matsuoka

Akihiro Tsujimura

Ichiro Seto

Takayoshi Ito

Syuichi Sekine

Osamu Shibata

Shoji Otaka

Hiroyuki Kayano

Shuichi Obayashi

Kazuhiro Inoue

Takafumi Yamaji

Keiichi Yamaguchi

Naoko Ono

Yuji Iseki

Hisao Iwasaki

Noriaki Odachi

Shu-ichi Sekine

Takayoshi Itoh

To provide a pharmaceutical composition which can enhance the storage stability of 1-(1-hydroxymethyl-2,3-dihydroxypropyloxymethyl)-2-nitroimidazole without impairing the effect of the compound. The pharmaceutical composition includes 1-(1-hydroxymethyl-2,3-dihydroxypropyloxymethyl)-2-nitroimidazole, which is represented by formula (1): and a compound having chelating ability.

Pharmaceutical composition

To provide a pharmaceutical composition containing a 2-nitroimidazole derivative, which has high solubility in an aqueous carrier and high stability. The pharmaceutical composition is characterized by containing 1-(1-hydroxymethyl-2,3-dihydroxypropyl)oxymethyl-2-nitroimidazole and creatinine, and containing creatinine of 0.001 to 1 part by mass with respect to 1 part by mass of 1-(1-hydroxymethyl-2,3-dihydroxypropyl)oxymethyl-2-nitroimidazole.

A Cancer radiotherapeutic method using 1-(1-hydroxymethyl-2,3-dihydroxypropyl)oxymethyl-2-nitroimidazole (compound (i), and creatinine in an amount of 0.001 to part by mass with respect to 1 part by mass of compound (1); and irradiation.

There is disclosed a radio communication system in which a constitution of a base station and further a control station can be simplified. A radio communication system according to the present invention converts a received signal received by a plurality of antenna elements in a base station to a signal of different frequency band, and then conflates the converted signal in order to generate sub-carrier wave multiplex signal. The signal is converted to an optical signal, and then the optical signal is transmitted to a control station via an optical fiber. Or the control station performs weighting to phase of the transmitted signal transmitted from a plurality of antennas of a base station, and then performs frequency conversion to different frequency band, and then conflates the converted signal in order to generate the sub-carrier wave multiplex signal. The signal is converted to an optical signal, and then an optical signal is transmitted to the base station side via the optical fiber. The control station and the base station divides the received sub-carrier wave multiplex signal by each frequency band, and then the frequency of the divided signals are converted to the same frequency band in order to generate the transmitted/received signal of each antenna element. By such a constitution, it is possible to reduce constituent of the optical transmission components to the minimum and to simplify the constitution of the base station. Furthermore, it is possible to maintain the relative phase difference and the relative intensity of the transmitted/received signal of each antenna element. Because of this, it is possible to estimate an arrival direction of the received signal and to control radiation beam pattern of the transmitted signal.

Radio communication system

In a radio equipment of portable type, the impedance of an antenna is optimized by adjusting a matching circuit which has the adjustment function and is connected to an antenna, based on a reflection phase sent back from the antenna, outputted from a reflection phase detector, and a current supplied to a transmitter-receiver which generates a transmitting signal.

Portable type radio equipment

An antenna apparatus is constituted by first, second, third, and fourth wire antenna elements and a connection element. The sum of the lengths of the first, second, and fourth wire antenna elements is &#xbc; the wavelength corresponding to a series-resonance frequency of the first, second, and fourth wire antenna elements. The sum of the lengths of the second, third, and fourth wire antenna elements is &#xbd; the wavelength corresponding to a parallel-resonance frequency of the second, third, and fourth wire antenna elements. The sum of the lengths of the first and third wire antenna elements is &#xbc; the wavelength corresponding to a series-resonance frequency of the first and third wire antenna elements. The parallel-resonance frequency is higher than the series-resonance frequency of the first, second, and fourth wire antenna elements and lower than the series-resonance frequency of the first and third wire antenna elements.

Antenna apparatus

An antenna apparatus is constituted by first, second, third, and fourth wire antenna elements and a connection element. The sum of the lengths of the first, second, and fourth wire antenna elements is &frac14; the wavelength corresponding to a series-resonance frequency of the first, second, and fourth wire antenna elements. The sum of the lengths of the second, third, and fourth wire antenna elements is &frac12; the wavelength corresponding to a parallel-resonance frequency of the second, third, and fourth wire antenna elements. The sum of the lengths of the first and third wire antenna elements is &frac14; the wavelength corresponding to a series-resonance frequency of the first and third wire antenna elements. The parallel-resonance frequency is higher than the series-resonance frequency of the first, second, and fourth wire antenna elements and lower than the series-resonance frequency of the first and third wire antenna elements.

An active array antenna system comprises a plurality of element antennas and radio frequency circuits connected to the element antennas. The radio frequency circuits comprises first frequency converters provided to correspond to the element antenna and converts the frequency between a carrier-wave frequency and a first intermediate-frequency by using a carrier-wave frequency band local signal, second frequency converters provided to correspond to the element antenna and converts the frequency between the first intermediate-frequency signal and a second intermediate-frequency which is lower than the first intermediate frequency by using an intermediate-frequency band local signal, and a variable phase shifter circuit for individually controlling the phases of the intermediate-frequency local signals which are supplied to the second frequency converters. A variable phase shifter circuit for beam scan can be constituted at a low cost so that an active array antenna system which can be realized at a low cost is provided.

Active array antenna system

A patch having a circular shape for instance is formed on the main surface of a substrate in the shape of, for example, an equilateral triangle. The center of the main surface of the patch is at a position different from the center of the substrate. A grounding conductor is disposed on the backside of the substrate. Power is supplied to the patch through, for example, a microstrip line, triplate line, coplanar waveguide, slot line or the like. An antenna configured as described above has the center of the patch at a position different from the center of the triangle substrate, so that beams can be tilted in a desired direction by a single patch and a single feeder circuit.

Antenna capable of tilting beams in a desired direction by a single

An adaptive antenna is disclosed, that comprises a plurality of antenna elements 1.sub.1, 1.sub.2, . . . , and 1.sub.N with different directivity, delay profile measuring units 2.sub.1, 2.sub.2, . . . , and 2.sub.N for estimating states of received signals of the antenna elements for each of delay times that have been designated, antenna selecting units 3.sub.1, 3.sub.2, . . . , and 3.sub.L for selecting a part of the antenna elements for each of the delay times corresponding to the estimated result, adaptive signal processing portions 4.sub.1, 4.sub.2, . . . , and 4.sub.L for determining the received signals of the part of the antenna elements that have been selected and multiplying the received signals to which relevant weights have been determined for each of the delay time and summing the weighted signals, delaying circuits 5.sub.2 and 5.sub.3 for compensating the time lag, or delay of each of the received signals for each of the delay times, and a combining unit 6 for combining the weighted signals that have been compensated for the delay times.

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Yokohama, Japan

Yasushi Murakami