Takeda Chemical Industries, Inc.

Yasushi Mikura

Hisayoshi Shimizu

Akihiro Nagai

Hiroshi Fujisawa

Yoshiharu Matukura

Yasuo Doi

An injectable solution of a compound useful as an anti-ulcer agent of the formula; ##STR1## wherein R.sup.1 represents hydrogen, methoxy or trifluoromethyl group; R.sup.2 and R.sup.3, being the same as or different from each other, represent hydrogen or methyl group; and R.sup.4 represents a fluorinated C.sub.2 to C.sub.5 lower alkyl group, is provided by dissolving the compound in at least one of ethanol, propylene glycol and polyethylene glycol; or by dissolving the freeze-dried material of an alkaline aqueous solution of the compound in a mixture of an acidic substance and at least one of the above solvents.

Injectable solution containing a pyridyl methylsulfinylbenzimidazole

An antibiotic composition which comprises 7.beta.-[(Z)-(5-amino-1,2,4-thiadiazol-3-yl)-2(Z)-methoxyiminoacetamide]-3 (1-imidazo[1,2-b]pyridazinium)-methyl-3-cephem-4-carboxylate hydrochloride and a pharmaceutically acceptable water-soluble basic substance, which is stable in storage and improved in solubility as well as free of local actions or hemolytic action.

Antibiotic composition

An injectable solution containing a trihydric to hexahydric sugar alcohol together with L-pyroglutamyl-L-histidyl-L-prolinamide or a physiologically acceptable salt thereof shows significantly reduced pain when administered to a host, especially subcutaneously or intramuscularly.

Growing community of inventors

Osaka, Japan

Yasushi Mikura