Sumitomo Chemical Company, Limited

Yasushi Matsuki

Yoshiyasu Yabusaki

Shinji Hourai

Koji Hayashi

The present invention relates to an isolated or modified esterase having the excellent thermostable property which can be utilized for ester hydrolysis reaction, ester synthesis reaction, ester interchange reaction and its gene. The esterase is characterized in that it has at least a partial amino acid sequence necessary for expressing the thermostable esterase activity among the amino acid sequence shown by SEQ ID NO: 2 and further has an amino acid substitution described herein.

Thermostable esterase and its gene

A flavin-containing monooxygenase comprising the amino acid sequence of SEQ ID NO:8, a microorganism producing said flavin-containing monooxygenase, a flavin-containing monooxygenase gene containing a DNA sequence coding for the amino acid sequence of SEQ ID NO:8, a flavin-containing monooxygenase gene containing the DNA sequence of SEQ ID NO:7, a plasmid containing said flavin-containing monooxygenase gene, a microorganism containing said plasmid, and a method for producing the enzyme of the present invention wherein said microorganism is cultured to produce the enzyme.

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Ashiya, Japan

Yasushi Matsuki