Ihara Chemical Industry Co., Ltd.

Yasuo Yoshida

Yusuke Hamada

Kentaro Kawazoe

Yoshikazu Kimura

Kazuto Umezu

Fumiya Tabuchi

Hiroaki Takeuchi

A process for producing a 2-benzylphenol compound represented by the following formula (2): wherein, R, R, Rand Rmay be the same or different and are each independently hydrogen atom, alkyl group or the like; and R, R, R, Rand Rare the same or different and are each independently hydrogen atom, alkyl group or the like, the process including reacting, in the presence of a dehydrogenating agent, a benzylidenecyclohexanone compound represented by the following formula (1): wherein, R, R, R, R, R, R, R, Rand Rhave the same definitions as given above.

Process for production of 2-Benzylphenol compound

N-Cyclopropyl-2-difluoromethoxy-3-halogenoanilines which serve as important intermediates in the preparation of quinolonecarboxylic acids useful as synthetic antimicrobial agents from industrially inexpensive and easily available raw materials; and intermediates for the preparation thereof. Specifically, compounds represented by the general formula (1), (2) and (3),

N-cyclopropyl-2-difluoromethoxy-3-halogenoanilines and intermediates for the preparation thereof

Process for production of N-cyclopropylanilines and intermediates

Process for production of 1-alkoxy-1-trimethylsilyloxy cyclopropanes

A fluorobenzoate having the formula: ##STR1## wherein X is a fluorine atom or a hydrogen atom, and R is an alkyl group.

Fluorobenzoates and process for their production

A process for producing a fluorobenzaldehyde of the formula: ##STR1## wherein X is a chlorine atom, a bromine atom or an iodine atom, n is an integer of from 1 to 5, and m is an integer of from 1 to 5, provided n.gtoreq.m, which comprises reacting a halogenated benzaldehyde of the formula: ##STR2## wherein X and n are as defined above, with a metal fluoride in the presence of a catalyst, wherein at least one member selected from the group consisting of quaternary phosphonium salts and quaternary ammonium salts is used as the catalyst.

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Shizuoka, Japan

Yasuo Yoshida