Kyowa Hakko Kogyo Co., Ltd.

Yasuo Onoda

Haruki Takai

Akio Ishii

Katsushige Gomi

Daisuke Machii

Iwao Kinoshita

Koji Yamada

Makoto Morimoto

Tetsuji Ohno

Katsuichi Shuto

Michio Ichimura

Nobuo Kosaka

Hiroyuki Ishida

Hiroshi Kase

Yuji Nomoto

Joji Nakamura

Shin-ichi Sasaki

Nobuo Kasaka

Imidazoquinazoline derivatives

A triphenylmethane derivative represented by the following general formula: ##STR1## exhibits bone absorption inhibiting effects and is useful as a medicament for treating osteoporosis.

Triphenylmethane derivatives

There is provided a pyridine derivative represented by the formula (I) ##STR1## wherein each of R.sup.1 and R.sup.2 independently represents hydrogen or lower alkyl and each of R.sup.3 and R.sup.4 independently represents hydrogen, lower alkyl, alicyclic alkyl, substituted or unsubstituted polycyclic alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heterocyclic group, or R.sup.3 and R.sup.4 are combined with nitrogen atom adjacent thereto to form a substituted or unsubstituted alicyclic heterocyclic group, or pharmaceutically acceptable salt thereof. The pyridine derivative exhibits bone resorption inhibiting effect and is useful as a medicament for treating osteoporosis.

Pyridine derivatives

A triphenylmethane derivative represented by the following general formula: ##STR1## exhibits born absorption inhibiting effects and is useful as a medicament for treating osteoporosis.

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Shizuoka, Japan

Yasuo Onoda