Chugai Seiyaku Kabushiki Kaisha

Yasuo Nishii

Hideo Miyakoshi

Yoshihei Hirasawa

Tadao Aoki

Takao Aoki

A method for suppressing abnormal rise in immunological function which often causes various types of autoimmune diseases, and an agent useful therefor are disclosed. The method is carried out by administering cholecalciferol or its derivative to patients suffering from abnormal rise in immunological function. The agent contains the above compound as active ingredient and is useful not only to treat and/or prevent the abnormal rise in immunological function but also to suppress graft rejection.

Method for suppressing abnormal rise in immunological function and agent

A method for inhibiting the lowering of immunological function of patients who are suffering from serious renal disorder such as chronic renal failure or uremia which comprises administering 1.alpha.-hydroxycholecalciferol to the patients is disclosed. An agent useful in the practice of the method is also disclosed.

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Tokyo, Japan

Yasuo Nishii