Kabushiki Kaisya Advance Kaihatsu Kenkyujo

Kabushiki Kaisha Advance Kaihatsu Kenkyujo

Kabushiki Kaisya Advance Kaithatsu Kenkyujo

Yasuo Kawai

Kazunaga Yazawa

Kazuoki Ishihara

Hirotaka Shimohashi

Nobuo Suegara

Yoshiaki Oshida

An anticariogenic or antiperiodontitic agent containing, as an active component, yeast cells and/or water-soluble extracts of yeasts having antibacterial activity against Streptococcus mutans or Bacteroides gingivalis. This anticariogenic or antiperiodontitic agent has strong inhibitory effects on the growth of Streptococcus mutans causing dental caries and Bacteroids gingivalis causing periodontitis and has neither influence on intestinal microflora nor any side-effects when orally administered.

Anticariogenic or antiperiodontitic agent

An anticariogenic or antiperiodontitic agent containing, as an active component, adenosine or its derivatives having an antibacterial activity against Streptococcus mutans or Bacteroides gingivalis. This anticariogenic or antiperiodontitic agent has strong inhibitory effects on the growth of Streptococcus mutans causing dental caries and Bacteroides gingivalis causing periodontitis and has neither influence on intestinal microflora nor any side-effects when orally administered.

Anticariogenic or antiperidontitic method

Hypocholesterolemically and/or hypotriglyceridemically active RNA fractions having the following characteristics:

Hypocholesterolemically and/or hypotriglyceridemically active RNA

Hypocholesterolemically active RNA fractions having the following characteristics:

Hypocholesterolemically active RNA fractions

A hypocholesterolemically active protein capable of reducing the blood cholesterol in mammals having the following characteristics:

Hypocholesterolemically active protein derived from streptococcus

A bacterial cell product orally administered to lower serum cholesterol and/or triglyceride level in mammals obtained by cultivating a microorganism belonging to the genus Streptococcus and having a N-acetyl-.beta.-D-glucosaminidase activity in an adequate culture medium therefor, and collecting the cultivated microorganism from the resultant culture.

Hypocholesterolemically and/or hypotriglyceridemically active products

An anticariogenic or antiperiodontitic agent containing, as an active component, the bacterial cells and/or water-soluble extracts of a microorganism belonging to the genus Streptococcus or the genus Lactobacillus having antibacterial activity against Streptococcus mutans or the genus Bacteriodes. This anticariogenic or antiperiodontitic agent has strong inhibitory effects on the growth of Streptococcus mutans causing dental caries and Bacteroides causing periodontitis and has no influence on intestinal microflora when orally administered.

An intestinal microflora-improving agent containing, as an effective component, bacterial cells and/or the water-soluble extracts therefrom, obtained from microorganisms belonging to the genus Streptococcus.

Intestinal microflora-improving agent

A hypotriglyceridemically active polysaccharide having the following characteristics:

Hypotriglyceridemically active polysaccharides

A bacterial cell product having hypocholesterolemic and/or hypotriglyceridemic activity in mammals obtained by cultivating a microorganism belonging to the genus Streptococcus and having a N-acetyl-.beta.-D-glucosaminidase activity in an adequate culture medium therefor, and collecting the cultivated microorganism from the resultant culture.

Growing community of inventors

Atsugi, Japan

Yasuo Kawai