Nec Corporation

Yasuo Iimura

Minoru Asogawa

Yoshinori Mishina

Hisashi Hagiwara

Asumi Inaguma

There is provided a microchip useful for re-examination of a DNA analysis result. The microchip comprises a DNA analysis part configured to analyze DNA, which comprises at least a cell lysis chamber for cell lysis and a DNA extraction chamber which is connected to the cell lysis chamber and configured to extract DNA from lysed cells, and a DNA preservation part which is connected to the DNA analysis part via a flow path and configured to preserve a partial portion of a DNA sample.

Microchip

A microchip includes a cell accepting section, a lysis solution chamber and a lysis reaction chamber. The cell accepting section accepts cells obtained from a subject. The lysis solution chamber stores lysis solution for lysis of the cells. The lysis reaction of the cells is executed in the lysis reaction chamber.

Microchip, microchip controlling apparatus and microchip controlling system

A microchip controlling system comprises a microchip which is configured by adhesion of an elastic sheet and a plate/sheet member, and on which a flow path is provided as an inadhesive section between the elastic sheet and the plate/sheet member; and a microchip controlling apparatus comprising a valve mechanism which is inflated or deflated so as to control the flow path to be opened or closed.

Microchip controlling system

A microchip includes a plurality of laminated elastic sheets. Each of the elastic sheets forming a first intermediate layer as an intermediate layer formed with the plurality of elastic sheets have an inadhesive section(s) for forming a first flow path on the first intermediate layer. Each of the elastic sheets for forming a second intermediate layer as an intermediate layer formed with the plurality of elastic sheets have an inadhesive section(s) for forming a second flow path on the second intermediate layer. An elastic sheet(s) interposed between the first and second intermediate layers has a connecting section(s) connecting the first flow path and the second flow path. A flow path width at the connecting section(s) of the first flow path is narrower than a flow path width at the connecting section(s) of the second flow path.

Microchip, liquid transfer method and microchip controlling apparatus

Microchip, microchip controlling apparatus and microchip controlling system technical field

A microchip comprises a DNA analysis part configured to analyze DNA, which comprises at least a cell lysis chamber for cell lysis and a DNA extraction chamber which is connected to the cell lysis chamber and configured to extract DNA from lysed cells, and a DNA preservation part which is connected to the DNA analysis part via a flow path and configured to preserve a partial portion of a DNA sample.

A microchip comprises a plurality of laminated elastic sheets, wherein the elastic sheets are partially inadhesive each other so that at least 3 middle layers are formed; as a first middle layer, first flow path and second flow path through which liquid flows are formed; as a second middle layer, a first flow path opening/closing section for opening and closing the first flow path is formed; and as a third middle layer, a second flow path opening/closing section for opening and closing the second flow path is formed.

Microchip, microchip controlling method and microchip controlling apparatus

A microchip comprises a PCR section, a denaturing section, and an electrophoresis section. In the PCR section, a desired region in DNA is amplified. In the denaturing section, PCR amplicon of double-strand DNA is denatured into single-strand DNA. In the electrophoresis section, the PCR amplicon is separated based on the length of sequence.

Microchip, DNA analysis method and DNA analysis system

The present invention provides a chip for analysis of a target substance that is compact and allows analysis of a target substance with less time and effort. The chip for analysis of a target substance includes a first flexible substrate, a second flexible substrate, and a third substrate. A flow channel-forming non-bonded areais formed on a bonding surface of the first flexible substrateand the second flexible substratein a band-like manner and an extraction chamber-forming non-bonded areahaving a wider band width than the flow channel-forming non-bonded areais formed at a part of the flow channel-forming non-bonded area. The first flexible substrateincludes a through-holethat is in contact with the flow channel-forming non-bonded area, a shutter-forming non-bonded areais formed on a bonding surface of the second flexible substrateand the third substrateat a far side of the through-holerelative to the extraction chamber-forming non-bonded areasuch that the shutter-forming non-bonded areaand the flow channel-forming non-bonded areaintersect above and below, the first flexible substrateand the second flexible substrateinclude a pressure supply portthat comes through the substrates so as to be in contact with the shutter-forming non-bonded area, and a magnetic particlethat binds to a target substance is placed above the extraction chamber-forming non-bonded area

Chip for analysis of target substance

An analysis chip device according to an exemplary embodiment of the present invention includes a placing board () on which a microchip () is placed, and a coupling () attached to a cover () of the microchip (). The coupling () includes a linear electrode (), a sleeve () including an attach part () that is attached to the cover () and an air core part () in which the electrode () is provided, the sleeve () having a side surface in which an inlet port () is provided, the inlet port () communicating with the air core part (); and a holder () including a pipe connection part () to which a pipe () is connected, the pipe () supplying gas to the inlet port (), the holder () holding the sleeve () so as to surround the inlet port ().

Growing community of inventors

Tokyo, Japan

Yasuo Iimura