Hisamitsu Pharmaceutical Company, Inc.

Yasunari Michinaka

Yuka Takagi

Takito Shima

Hideaki Ohashi

Naoyuki Uchida

Naoko Fujita

Naruhide Miyoshi

Ryo Tanaka

Tomohiro Shinoda

Masaki Yukuhiro

Hisakazu Kurita

Kenji Ishigaki

Eisuke Hatanaka

Ryusuke Fudoji

Kana Imamura

Shingo Somekawa

Junji Noguchi

Takuya Umemoto

Yuka Ansai

The patch of the present invention comprises a backing layer and an adhesive layer laminated on the backing layer, wherein a water vapor transmission rate of the backing layer is 400 g/m·24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive. Such a patch does not fall off easily even after long wear.

Patch with DMSO in adhesive layer

An object of the present invention is to provide an asenapine-containing patch having excellent sustained-release properties while enhancing skin permeability by using a silicone-based pressure-sensitive adhesive base. The present invention relates to a patch having a support and a pressure-sensitive adhesive layer, wherein the pressure-sensitive adhesive layer comprises asenapine and/or a pharmaceutically acceptable salt thereof, a silicone-based pressure-sensitive adhesive base and a release control agent, and the ratio of the maximum skin permeation rate of asenapine to the minimum skin permeation rate from the time when the maximum skin permeation rate is reached to 24 hours is less than 1.62.

Asenapine-containing adhesive patch

Patch and package thereof

The patch of the present invention comprises a backing layer and an adhesive layer laminated on the backing layer, wherein a water vapor transmission rate of the backing layer is 400 g/m&#xb7;24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive. Such a patch does not fall off easily even after long wear.

Drug-containing patch

The present invention provides a patch comprising a backing and an adhesive agent layer laminated on the backing, wherein the adhesive agent layer comprises ropinirole or a pharmaceutically acceptable salt thereof, an organic amine or an acid addition salt thereof, and an adhesive agent.

Transdermal patch containing ropinirole

The present invention provides a topical preparation for treating hyperhidrosis, comprising water, an anticholinergic drug, and one or more salts selected from the group consisting of lactate, tartrate, acetate and phosphate. Such a topical preparation comprises the above certain salt, thereby facilitating the accumulation of the anticholinergic drug in skin appendages.

External agent for treating hyperhidrosis

A patch including: a support; and an adhesive layer disposed on at least one surface of the support, in which the adhesive layer includes: at least one selected from the group consisting of butorphanol and pharmaceutically acceptable salts thereof; a higher aliphatic alcohol; and a non-cross-linking polyvinylpyrrolidone that does not contain vinyl acetate as a constituent monomer thereof.

Patch

A patch comprising a support layer and an adhesive agent layer, wherein the adhesive agent layer comprises at least one drug selected from the group consisting of emedastine and pharmaceutically acceptable salts thereof, at least one adhesive agent selected from the group consisting of rubber-based adhesive agents and silicone-based adhesive agents, and an alkali metal fumarate as a cohesive force-improving agent for the adhesive agent layer.

Provided is a patchcontaining a backing layerand a pressure-sensitive adhesive layerformed on the backing layer, where the pressure-sensitive adhesive layercontains (i) ropinirole and a metal salt produced by the reaction of a ropinirole acid adduct and a metal ion containing desalting agent in an equivalent mole or less to the acid adduct and (ii) an adhesive base free of a hydroxyl group and a carboxy group.

Adhesive skin patch and packaged product

A ropinirole-containing patch comprises an adhesive agent layer and a support layer, the adhesive agent layer containing ropinirole and/or a pharmaceutically acceptable salt thereof, wherein

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Tsukuba, Japan

Yasunari Michinaka