Daiichi Sankyo Company, Limited

Yasuki Kamai

Atsushi Urano

Jun Hasegawa

Takako Kimura

Toshinori Agatsuma

Toshiaki Ohtsuka

Tatsuji Matsuoka

Yumi Matsui

Chigusa Yoshimura

Reimi Kawaida

Chiaki Ishii

Teiji Wada

Saori Ishida

Tomomi Iwata

A pharmaceutical composition and a therapeutic method wherein an antibody-drug conjugate and an immune checkpoint inhibitor are administered in combination, and the antibody-drug conjugate is an antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents the connecting position to an antibody) is conjugated to the antibody via a thioether bond; and a pharmaceutical composition and a therapeutic method for use in treatment of a disease that can be ameliorated through an antitumor immunity-activating effect wherein the antibody-drug conjugate is included.

Combination of antibody-drug conjugate and immune checkpoint inhibitor

A pharmaceutical composition and a therapeutic method wherein an antibody-drug conjugate and an immune checkpoint inhibitor are administered in combination, and the antibody-drug conjugate is an antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents the connecting position to an antibody) is conjugated to the antibody via a thioether bond; and a pharmaceutical composition and a therapeutic method for use in treatment of a disease that can be ameliorated through an antitumor immunity-activating effect wherein the antibody-drug conjugate is included. 

The present invention provides a combination of an antibody binding to a fibroblast growth factor receptor, and another agent.

Combination comprising anti-fibroblast growth factor receptor 2 (FGFR2) antibody and a tyrosine kinase inhibitor

The present invention provides an antibody which binds to a fibroblast growth factor receptor.

Anti-FGFR2 antibodies and methods of use thereof for treating cancer

Anti-FGFR2 antibodies and pharmaceutical compositions thereof

Growing community of inventors

Tokyo, Japan

Yasuki Kamai