Chugai Seiyaku Kabushiki Kaisha

Tohoku Ricoh Co., Ltd.

Japan Spectroscopic Co., Ltd.

Yasuhiro Tsuji

Kiyoshige Wakabayashi

Mitsuo Otsuka

Keiichi Kamisango

Mitsuo Watanabe

Ikue Kawashima

Masafumi Kumano

Hideki Konishi

Shigeyuki Kimura

Masayuki Hirama

A method for assay of an analyte by use of a material labeled with a chemiluminescent substance, which comprises adding a quencher and/or decreasing the specific activity of a chemiluminescent substance labeled probe, thereby decreasing the quantity of chemiluminescence.

Method for assay of analyte by adjustment of chemiluminescence

Method of assaying specimen substance by controlling dose of

A vascular anastomosis apparatus using a carbon dioxide laser is proposed. The vascular anastomosis apparatus satisfies three conditions: a long focal distance of not less than 10 cm which is suitable for surgical operations under microscopic observation; a beam spot diameter of 0.1 to 0.3 mm when a laser beam is converged; and a stable, small beam output of not more than 100 mW. A visible guide beam having the same focusing point as that of the carbon dioxide laser beam is used in the vascular anastomosis apparatus.

Vascular anastomosis apparatus

A technique for measuring the degree of an antigen-antibody reaction by preparing a suspension of insoluble microscopic carrier particles of at least one type carrying an antigen, an antibody or a hapten, forming an agglutination promoting or inhibiting reaction system among the insoluble carrier particles based on an antigen-antibody reaction using the suspension and one or more antigen, antibody or hapten, irradiating the solution of the reaction system with laser light and detecting the light scattered from the reaction system at one or more specific angles, detecting a signal indicative of one or more specific frequency bands from the resulting scatter spectrum, and thenceforth calculating the quantity of antigen, antibody or hapten in a specimen on the basis of the detected signal. The intensity spectrum output of filter 11 for frequency band selection is in the form of a square root and is converted into the original intensity spectrum by means of a squaring circuit 12. The output of the squaring circuit is recorded by a recorder 10.

Light scattering immunoassay involving particles with selective

An apparatus for taking up and discharging liquid has at least one piston cylinder which responds to a command by taking up or discharging liquid, the arrangement being such that the number of liquid uptake operations is preset, with the piston cylinder being instructed to perform the discharge operation when the number of uptake operations actually performed is detected to exceed said preset number. A plurality of different liquid specimens can be mixed, and the mixture diluted when so desired, through a simple operation which assures great accuracy.

Liquid uptake and discharge apparatus

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Saitama, Japan

Yasuhiro Tsuji