Nippon Paint Compnay, Ltd.

Yasuhiro Kinoshita

Yoshikazu Yamamoto

Yasutaka Miura

Takashi Yoshii

Masako Higuchi

Kunio Takahashi

Keisuke Tashiro

Kaoru Takatori

Kiyotaka Koyama

Stable and safe cosmetic compositions comprising melanin production inhibitors wherein the melanin production inhibitors have been extracted lichens cell cultures.

Cosmetics

Disclosed is a chemically stable tyrosinase activity inhibitor having high tyrosinase activity inhibition effect and low toxicity. The tyrosinase activity inhibitor has a structure of the formula: ##STR1## wherein R.sub.1, R.sub.3 and R.sub.4 are a hydrogen atom or an alkyl or alkenyl group having 1 to 9 carbon atoms, and R.sub.2 is an alkyl or alkenyl group having 2 to 9 carbon atoms.

Tyrosinase activity inhibitor

The present invention provides a dye other than red and purple which is obtained from cultured cells of Euphorbia milli. The present invention also provides cultured cells containing quercetin glucuronide in a large amount, derived from tissues or cells of Euphorbia milli.

Production of quercetin glucuronide

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Neyagawa, Japan

Yasuhiro Kinoshita