Kabushiki Kaisha Toshiba

Msd K.k.

Merck Sharp + Dohme Corp.

Banyu Pharmaceutical Co. Ltd

Seikagaku Corporation

Yasuhiro Goto

Koichiro Akiyama

Takayuki Fukasawa

Seiichi Suenaga

Maki Yonetsu

Kenji Essaki

Yoshihiko Nakano

Toshihiro Sakamoto

Hidetomo Furuyama

Takashi Kuboki

Koichi Harada

Kenji Niiyama

Keiji Takahashi

Satoshi Sunami

Masahiro Kato

Yasushi Hattori

Tomokazu Morita

Norihiro Tomimatsu

Makoto Bamba

Takeshi Sagara

Hiroshi Hirai

Fuyuki Yamamoto

Takashi Yoshizumi

Sachie Otsuki

Takeyuki Yonezawa

Toshihide Nishibata

Yumi Fukuda

Keiko Albessard

Mark E Layton

Philip E Sanderson

Yoshio Ogino

Jiabing Wang

Shinichi Onodera

Nobuhiko Kawanishi

Takashi Mita

Hideyuki Oozu

Yu Onozaki

Yoshiyuki Ohnuma

Hiroki Inagaki

Shinsuke Matsuno

Jun Tamura

Yasuyuki Hotta

Toshiro Hiraoka

Michiyasu Komatsu

Masahiro Takashita

Tomohiro Suetsuna

Yuichi Komano

Akihiko Tsuge

Takashi Yamauchi

Kunihiko Wada

Tsuneji Kameda

Shoko Suyama

Kazuhiro Yasuda

Hideyuki Ohzu

Mitsuhiro Oki

Hidehiko Kobayashi

Miho Maruyama

Akira Naya

Michael A Rossi

Kevin J Rodzinak

Toshiaki Mizutani

Takahiro Hatanaka

Toshiaki Nakagawa

Jen Ando

Tomochika Kisukeda

Yuichi Chikaraishi

According to one embodiment, a structure according to the embodiment includes a β type silicon nitride type crystal phase and a YSiONtype crystal phase. In an X-ray diffraction pattern according to a θ-2θ method of the structure, a ratio of a second peak intensity being maximum and appearing at 2θ=31.93±0.1° with respect to a first peak intensity being maximum and appearing at 2θ=27.03±0.1° is 0.005 or more and 0.20 or less.

Structure and bonded body

A structure according to the embodiment includes a first crystal grain, a second crystal grain, and a first region. The first crystal grain includes silicon nitride. The second crystal grain includes a first element selected from a first group consisting of scandium, yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, aluminum, chromium, zirconium, magnesium, zinc, titanium, gallium, beryllium, calcium, strontium, barium, hafnium, vanadium, niobium, tantalum, tungsten, iron, cobalt, nickel, and copper, and oxygen. The first region includes an oxide of the first element.

Structure and circuit board

A structure includes: a &#x3b2; silicon nitride crystal phase; and a YMgSiON crystal phase. The structure gives a X-ray diffraction pattern by a &#x3b8;-2&#x3b8; method, the pattern having a ratio of a peak intensity of a (22-1) plane of the YMgSiON crystal phase to a peak intensity of a (200) plane of the &#x3b2; silicon nitride crystal phase, the peak intensity of the (200) plane being determined at a position of 2&#x3b8;=27.0&#xb1;1&#xb0;, the peak intensity of the (22-1) plane being determined at a position of 2&#x3b8;=30.3&#xb1;1&#xb0;, and the ratio being 0.001 or more and 0.01 or less.

Structure and joined composite

Provided are a composition comprising a GAG derivative and a chemokine receptor activity regulator, and a pharmaceutical composition comprising said composition.

Composition including glycosaminoglycan derivative and chemokine receptor activity regulator

The active material for a nonaqueous electrolyte secondary battery of the present embodiment includes a core particle and a carbon layer. The core particle is formed of silicon particles having a twinned crystal in part of a surface. The carbon layer coats the core particle.

Active material, electrode, nonaqueous electrolyte secondary battery, battery pack and production method of active material

A fuel synthesis catalyst of an embodiment for hydrogenating a gas includes at least one selected from the group consisting of; carbon dioxide and carbon monoxide, the catalyst comprising, a base material containing at least one oxide selected from the group consisting of; AlO, MgO, TiO, and SiO, first metals containing at least one metal selected from the group consisting of; Ni, Co, Fe, and Cu and brought into contact with the base material, and a first oxide containing at least one selected from the group consisting of; CeO, ZrO, TiO, and SiOand having an interface with each of the first metals and the base material. The first metals exist on an outer surface of the base material, and on a surface of the base material in fine pores having opening ends on the outer surface of the base material and inside the base material. The first metals and the first oxide exist in the fine pores. The first metals have interfaces with the base material in the fine pores. The first metals exist inside the base material.

Fuel synthesis catalyst and fuel synthesis system

An electrode material for nonaqueous electrolyte secondary battery of an embodiment includes a silicon nanoparticle, and a coating layer coating the silicon nanoparticle. The coating layer includes an amorphous silicon oxide and a silicon carbide phase. At least a part of the silicon carbide phase exists on a surface of the silicon nanoparticle.

Electrode material for nonaqueous electrolyte secondary battery, electrode for nonaqueous electrolyte secondary battery, and nonaqueous electrolyte secondary battery

A negative electrode active material for a nonaqueous electrolyte secondary battery of an embodiment includes a carbonaceous material, a silicon oxide phase in the carbonaceous material, and a silicon phase in the silicon oxide phase. The negative electrode active material has a crack in the carbonaceous material, and the longest side of the crack has a length equal to or greater than &#x2155; of the diameter of the negative electrode active material.

Negative electrode active material for nonaqueous electrolyte secondary battery, nonaqueous electrolyte secondary battery, and battery pack

In a symmetric encryption apparatus according to an embodiment, a storage unit stores a symmetric key formed from a plurality of elements of a first polynomial ring. A plaintext acceptance unit accepts input of plaintext information. A plaintext polynomial generation unit generates a plaintext polynomial by embedding the plaintext information whose input has been accepted in at least one of terms of a polynomial in a subspace of the first polynomial ring. A mask polynomial generation unit generates a mask polynomial having the symmetric key as a solution based on a second commutative ring defined over the first polynomial ring. An encryption unit generates a ciphertext using the plaintext polynomial and the mask polynomial.

Symmetric encryption apparatus and storage medium, and symmetric decryption apparatus and storage medium

A digital signature generation apparatus includes memory to store finite field Fand section D(u(s, t), u(s, t), s, t) as secret key, section being one of surfaces of three-dimensional manifold A(x, y, s, t) which is expressed by x-coordinate, y-coordinate, parameter s, and parameter t and is defined on finite field Fq, x-coordinate and y-coordinate of section being expressed by functions of parameter s and parameter t, calculates hash value of message m, generates hash value polynomial by embedding hash value in 1-variable polynomial h(t) defined on finite field F, and generates digital signature D(U(t), U(t), t) which is curve on section, the x-coordinate and y-coordinate of curve being expressed by functions of parameter t, by substituting hash value polynomial in parameter s of section.

Digital signature generation apparatus, digital signature verification apparatus, and key generation apparatus

The present invention aims to provide a fuel cell anode, a membrane electrode assembly and a fuel cell, so as to obtain high electric power. The fuel cell anode has an electrode catalyst layer, and the electrode catalyst layer comprises a supported catalyst comprises electrically conductive carriers and fine catalytic particles supported thereon, a proton-conductive inorganic oxide supporting SiOon its surface, and a proton-conductive organic polymer binder. The SiOsupported on the inorganic oxide prevents the oxide particles from growing, to ensure the high electric power. It is necessary to control the mixing ratios among the supported catalyst, the proton-conductive oxide and the proton-conductive binder in particular ranges.

Proton-conductive inorganic material for fuel cell and fuel cell anode employing the same

The invention relates to compounds of a general formula (I): wherein Aris an optionally-substituted aryl or heteroaromatic group; Ris an optionally-substituted lower alkyl, lower alkenyl, lower alkynyl or cyclo-lower alkyl group, or is an aryl, aralkyl or heteroaromatic group optionally having a substituent; Ris a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group, or is an aryl, aralkyl or heteroaromatic group optionally having a substituent; Ris a hydrogen atom or a lower alkyl group; Ris a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group or a group of &#x2014;N(R)R; T and U are a nitrogen atom or a methine group, etc. The compounds of the invention have excellent Weel kinase-inhibitory effect and are therefore useful in the field of medicines, especially treatment of various cancers.

Dihydropyrazolopyrimidinone derivatives

The carbon fibers of this invention is characterized in that irreducible inorganic material particles in a mean primary particle size below 500 nm and reducible inorganic material particles in a mean primary particle size below 500 nm were mixed by pulverizing and then, the mixture was heat treated under the reducing atmosphere and metal particles in a mean particle size below 1 &#x3bc;m were obtained, and the mixed powder of the thus obtained metal particles with the irreducible inorganic material particles are included in the carbon fibers.

Electrode catalyst material comprising carbon nano-fibers having catalyst particles on the surface and in the insides of the interior area and a fuel cell having the electrode catalyst material

The instant invention provides for substituted [1,2,4]triazolo[4,3-a]-1,5-naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms, preferably Akt1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity, especially Akt1 by administering the compound to a patient in need of treatment of cancer.

Inhibitors of AKT activity

Growing community of inventors

Tokyo, Japan

Yasuhiro Goto