Eisai Company, Limited

Yasuhiko Mizuno

Masanori Kayano

Sumio Watanabe

Yoshio Ishino

A soft-gelatin capsule having a coating film layer of carnauba wax on the outer surface of the soft-gelatin shell. Preferably, the amount of the carnauba wax is at least 0.002 part by weight based on 100 parts by weight of the amount of the soft-gelatin shell.

Soft capsule coated with a film of carnauba wax and process for the

A hollow particulate for gastric medicines and other durable medicines suspendable in the gastric juice and remainable in the stomach for a long period of time is provided which has been prepared by dissolving ethylcellulose in a lower chlorinated hydrocarbon, or a mixed solution of the lower chlorinated hydrocarbon and a lower chlorofluorinated hydrocarbon and/or water, so that the concentration of ethylcellulose is 0.5 - 4% by weight on the basis of the total weight of the resulting solution, and then spray-drying the solution at an inlet temperature of higher than 50.degree. C.

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Honjo, Japan

Yasuhiko Mizuno