Kaken Chemical Co., Ltd.

Yasuhiko Hamazaki

Toshiyuki Yamamoto

Nobuo Ishiyama

Reiko Sato

Kenji Seri

Shozo Kawabata

Akira Ueno

Yasuo Shiraishi

Masao Sakasai

Koji Amemiya

Katsumas Saga

Benzaminoethylphenoxycyclohexylacetic acid derivatives having the formula ##STR1## wherein R.sup.1 represents hydrogen atom, a halogen atom, hydroxyl group, a lower alkyl group or a lower alkoxy group; n is 1 or 2; and R.sup.2 represents hydrogen atom, a lower alkyl group which can have a substituent of phenyl group, a lower alkoxycarbonyl group, 3,3,5-trimethylcyclohexyloxycarbonyl group or a heterocyclic group; hexadecyl group; phenyl group which can have a substituent of a lower alkyl group, a lower alkoxy group, a lower alkoxycarbonyl group or a halogen atom; a cyclohexyl group or .alpha.-[4-(4-chlorobenzaminoethyl) phenoxy]-.alpha.-cyclohexylacetoxycyclohexyl group a antihyperlipidemic compositions thereof.

Benzaminoethylphenoxycyclohexylacetic acid derivatives

Novel substituted oxy-cyclohexylacetic acid derivatives as antihyperlipidemic agents are given. The compounds have the formula ##STR1## wherein n is 1 or 2; m is 0, 1 or 2; R.sub.1 represents a halogen atom, trifluoromethyl, a lower alkyl, a lower alkoxy, a lower alkylcarbonyl, dimethylphenylmethyl, cyclohexyl, phenyl, halogenophenyl, phenoxy or halogenophenoxy group, and two of R.sub.1 groups can be bonded to form an orthocondensed saturated alkylene ring; Hal represents a halogen atom; and R.sub.2 represents a hydrogen atom or a lower alkyl group.

Substituted oxy-cyclohexylacetic acid derivatives

Benzoyl phenoxy acetic acid derivatives having the formula ##STR1## wherein R.sub.1 represents hydrogen or halogen atom or a lower alkyl group or a lower alkoxyl group; and R.sub.2 represents hydrogen atom or a lower alkyl group which impart excellent antihyperlipidemic activity are provided.

Benzoyl phenoxy acetic acid derivatives

Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula ##STR1## WHEREIN R.sub.1 represents hydrogen, hydroxy, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,

Anti-inflammatory agent of benzoyl derivative

Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula ##STR1## WHEREIN R.sub.1 represents hydrogen, halogen, hydroxy, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,

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Yasuhiko Hamazaki