Jiangsu Academy of Agricultural Sciences

Yanyan Zhao

Xiao Zhang

Yuan Liu

Xianjin Liu

Chongxin Xu

Yajing Xie

Aihua Wu

Jianfeng Zhong

The present invention discloses a human-derived insecticidal gene and insecticidal peptide encoded by the same and application thereof. The nucleotide sequence of the human-derived insecticidal gene is as represented by SEQ ID NO.1. The amino acid sequence of the insecticidal peptide encoded by this gene is as represented by SEQ ID NO.2. The insecticidal peptide may be expressed through prokaryotic system. The primary culture has binding activity tomidgut peritrophic membrane specific receptor BBMV. It is obtained without animal immunization and has a short production cycle and a small amino acid sequence. It is suitable for in vitro mass production and may lower the safety risks resulting from wide use of existing Bt toxins and even might substitute Bt to biologically control agricultural pests in the future. It has important scientific and practical significance to reducing the use of insecticides.

Human-derived insecticidal gene and insecticidal peptide encoded thereby and application thereof

Growing community of inventors

Xuanwu Nanjing, China

Yanyan Zhao