Chinese Academy of Sciences

East China University of Science and Technology

Yunnan University

Yanyan Diao

Hualiang Jiang

Honglin Li

Zhenjiang Zhao

Weilie Xiao

Lili Zhu

Lina Quan

Qiao Li

Provided are use of a saponin compound of formula (I) or (II), or a pharmaceutically acceptable salt, prodrug or solvate thereof, in the manufacture of a medicament targeting PD-1. The medicament targeting PD-1 is one which treats a disease by inhibiting PD-1 from binding to a ligand thereof. The disease may be a tumor, an infection caused by a bacterium, a virus or a fungus, or an inflammatory disease. 

Saponin compound targeting PD-1 and application thereof

Growing community of inventors

Shanghai, China

Yanyan Diao