Shanghai Fochon Pharmaceutical Co., Ltd.

Fochon Pharmaceuticals, Ltd.

Chongqing Fochon Pharmaceutical Co., Ltd.

Chinese Academy of Sciences

Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

Fochon Biosciences, Ltd.

Fochon Pharmaceutical Co., Ltd.

Yanxin Liu

Weibo Wang

Xingdong Zhao

Xianlong Wang

Zuwen Zhou

Lihua Jiang

Jing Sun

Tongshuang Li

Haohan Tan

Zhifang Chen

Rui Tan

Ling Chen

Yue Rong

Zhifu Li

Qihong Liu

Qiang Tian

Huajie Zhang

Hongbin Liu

Lijun Yang

Min Lin

Chengxi He

Fanxin Zeng

Weipeng Zhang

Zongyao Zou

Li Linghu

Bin Liu

Kai Ran

Jiemin Fu

Bo Fang

Hailong Shi

Quan Yuan

Jian Ding

Meiyu Geng

Linghua Meng

Shu Lin

Yunling Wang

Yuwei Gao

Chuiliang Yu

Hong Fu

Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.

Apoptosis-inducing agents

Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.

Macrocyclic compounds as TRK kinases inhibitors

Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof are provided. In particular, Bcl-2 inhibitors of formula (I) are provided, wherein the variable groups are as defined in the specification. The Bcl-2 inhibitors can be used to treat cell proliferative disorders. 

Compounds as BLC-2-selective apoptosis-inducing agents

Certain CDK4/6 inhibitors and pharmaceutically acceptable salts thereof are described. In particular, these compounds can inhibit kinase activity of CDK4/6 and may be useful for the treatment of hyper-proliferative diseases like cancer and inflammation. In addition, the pharmaceutical compositions thereof and methods of use thereof are also described.

Certain protein kinase inhibitors

Provided are certain CDK4/6 inhibitors with the structure of formula (I), pharmaceutical compositions thereof, and methods of use therefor. The compounds are of the class of pyrimidin-2 amine derivatives, useful for the treatment of hyper-proliferative diseases. 

Certain protein kinase inhibitor

Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.

Provided are compound of formula (I) as certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use thereof. 

Disclosed herein are protein kinase inhibitors, more particularly novel quinazoline derivatives and pharmaceutical compositions thereof, and method of use thereof.

Quinazoline derivatives, compositions thereof, and use as pharmaceuticals

Disclosed herein are protein kinase inhibitors, more particularly pyridazine derivatives and pharmaceutical compositions thereof, and method of use thereof.

Growing community of inventors

Chongqing, China

Yanxin Liu