Empire Technology Development LLC

Other

Yansong Gu

William Brenden Carlson

Ivan Vesely

Marvi A Matos

Josef Peter Klein

Roger Alan Sahm

Floyd Brian Karp

Hongzhe Li

Luisa Mayorga Szott

Hongzho Li

Technologies are generally described for determination and analysis of an optical profile of a liquid-based material to implement real-time monitoring of a composition of the liquid-based material for quality control. An imaging sub-system may include a plurality of illumination sources configured to illuminate the liquid-based material with light, and one or more detectors. The detectors may be configured to detect light reflected from a first surface of the liquid-based material, light reflected from a second surface of the liquid-based material, and/or light transmitted through the first surface and the second surface of the liquid-based material in response to the illumination. An analytics sub-system coupled to the imaging sub-system may be configured to analyze the detected light to determine an optical profile of the liquid-based material, and monitor the optical profile in real-time to detect changes in the optical profile indicative of corresponding changes to a composition of the liquid-based material.

Real-time monitoring of material composition for quality control

Disclosed are methods and systems for testing the effects of various morphogens and/or feeder cells on the differentiation of pluripotent cells. The assays described herein can be used for determining the optimum conditions that lead to differentiation of stem cells. Once the optimum conditions for stem cell differentiation are determined, such cells may be used in a variety of therapies.

Methods and devices for high throughput screening of conditions affecting stem cell differentiation

Technologies are generally described for spectroscopic determination of one or more optical properties of a gemstone. An imaging device may include one or more light sources configured to illuminate one or more portions of the gemstone, and one or more photo detectors configured to detect reflected light from the portions of the gemstone in response to the illumination. An analysis module may be communicatively coupled to the imaging device, and configured to analyze the reflected light to determine the optical properties of the portions of the gemstone. The optical properties may include at least one of a clarity, color, fluorescence, birefringence, dichroism, and brilliance of the portions of the gemstone. In some examples, an optical fingerprint of the gemstone may be created based on one or more determined optical characteristics of the portions of the gemstone, where the optical fingerprint may uniquely identify the gemstone.

Spectroscopic determination of optical properties of gemstones

A method for the quality control of dairy products is disclosed. The method includes scanning the surface of a dairy product test sample using a chromatic scanner system to generate a spectral pattern of reflected light intensities, which pattern is unique to the test sample. The spectral pattern from the test sample is compared with spectral patterns from one or more reference dairy products to provide an indication of test sample identify, quality and/or nutritional content.

Quality control of dairy products using chromatic profiles

Paint configured to provide a hydrophilic paint surface comprising a paint base and a texture imprinting additive (TIA) that provides sacrificial particles upon drying of the paint. Loss of the sacrificial particles increases roughness and reduces the contact angle with water, providing a hydrophilic surface that is wettable and hence self-cleaning. Also described are specific types of TIA, methods of making the paint, methods of making a hydrophilic surface, and kits.

Composition of hydrophilic painted surface

The present invention provides methods to reduce or inhibit weight gain by administering inhibitors of the SirT1 protein to a subject. Methods to identify such inhibitors are also disclosed.

Methods for treating obesity

This disclosure relates generally to methods, apparatuses, and cellular compositions and cellular products that use a unique trophoblast-containing 3D matrix as a compartmental chamber for growing embryoid bodies that can be induced to differentiate into organ-specific cell types.

3D trophoblast matrix for preparing organ-specific stem cells

A lignin derivative including one or more polycations is provided and an article including such a lignin derivative is also provided. Methods of inhibiting microbial growth with an article including such a lignin derivative are further provided.

Lignin derivatives having polycations and uses thereof

A system includes a first chamber configured to receive a hydrogel and a scaffold comprising a cell, wherein the hydrogel is in fluid communication with the scaffold, and wherein the hydrogel includes a plurality of unidirectional pores. The system also includes a second chamber configured to receive a first fluid and a second fluid, wherein the second chamber includes a wall that separates the first fluid from the second fluid. The system further includes a porous membrane configured to separate the first chamber from the second chamber. The wall is configured to move along the porous membrane as cellular extensions are projected into at least a portion of the plurality of unidirectional pores of the hydrogel.

Bioreactor for controlling cellular growth

Block co-polymers including a hydrophilic block and a hydrophobic poly(amino acid) block which further includes dihydroxyphenyl moieties are provided, as well as methods of making and using the same. Such block copolymers may be used to prepare biocompatible adhesives which display good adhesives properties in aqueous environments, including in in vivo applications.

Biocompatible adhesive polymers

A system for generating a tissue construct includes a mixing chamber, a piston chamber, a reaction chamber, and a pump. The mixing chamber is configured to receive a hydrogel solution and a cell suspension solution. The piston chamber includes a first piston and is configured to receive a mixture of the hydrogel solution and the cell suspension solution from the mixing chamber. The first piston is configured to push the mixture through one or more capillaries into the reaction chamber. The reaction is configured to receive the mixture and a cross-linking initiator. The pump is configured to move the mixture through the reaction chamber such that the mixture and the cross-linking initiator combine to form an encapsulated cell material.

Bioreactor for engineered tissue

A block co-polymer includes a water soluble carrier block; an amino acid-based or acrylic acid-based block; and the amino acid-based or acrylic acid-based block includes a fluorinated alkyl group or a fluorinated alkylene glycol group.

Fluorinated block co-polymers

An article including a lignin derivative, where the lignin derivative includes a moiety derived from an antimicrobial compound. Also provided are methods of inhibiting microbial growth with an article including a lignin derivative.

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Bellevue, WA, United States of America

Yansong Gu