Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Centaurus Biopharma Co., Ltd.

Lianyungang Runzhong Pharmaceutical Co., Ltd.

Primegene (beijing) Co., Ltd.

Other

Powervision Robot Inc.

Primegene Co., Ltd.

Yanqing Yang

Li Zhu

Liguang Dai

Hui Zhang

Wei Wu

Xiaowei Duan

Wei Hu

Yong Peng

Yongxin Han

Yuandong Hu

Shanchun Wang

Ling Yang

Xin Tian

Rui Zhao

Weifeng Zheng

Yinghui Sun

Zhao Yang

Fansheng Kong

Baoyi Zhang

Hongjiang Xu

Na Zhao

Hong Luo

Fei Liu

Xijie Liu

Yizhong Zhu

Meng Guo

Lingjun Meng

Jiuqing Zhang

Changxin Dong

Zhaobai Zhong

Yangchun Wang

Hongjuan Li

Pyrazolopyrazine derived compounds as represented by general formulas (AI) and (I) or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an isotopic marker or an isomer thereof. Provided are a pharmaceutical composition comprising same and use of the compounds and the pharmaceutical composition in the preparation of medicaments for treating JAK kinase-mediated diseases. The compounds and pharmaceutical composition thereof provided have significant JAK kinase inhibitory activity, and in particular, have relatively high Tyk2 kinase inhibitory activity and selectivity for JAK2, and therefore have a very promising application potential.

Pyrazolopyrazine derived compounds, pharmaceutical composition and use thereof

Provided is a quinolyl-containing compound as shown in general formula (I) or (II) or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an isotopic label, or an isomer thereof, and further provided are a pharmaceutical composition comprising the compound and use of the compound and the pharmaceutical composition. The provided compound has a dual molecule function, can serve as multi-target inhibitors of novel tyrosine kinase/histone deacetylase, can simultaneously achieve the effect of two inhibitors, has excellent biological activity and pharmacokinetic properties, and has the application potential particularly in the field of treatment of tumors.

Quinolyl-containing compound and pharmaceutical composition, and use thereof

The present invention provides a compound as represented by formula (1) or a pharmaceutically acceptable salt, a solvate, an active metabolite, a polymorph, an isotope label, an isomer or a prodrug thereof. The present invention also provides a pharmaceutical composition containing the same and the use of the compound and the pharmaceutical composition in preparation of drugs for treating tyrosine kinase-mediated diseases. The compound and the pharmaceutical composition comprising same provided by the present disclosure have significant tyrosine kinase inhibitory activity, can overcome tumor drug resistance, and break through blood-brain barrier, also have excellent pharmacokinetic properties and excellent oral bioavailability, and can be administered in a small dosage, thereby reducing treatment costs and possible side effects to a patient. Thus, the application potential is very great.

Diaryl macrocyclic compound and pharmaceutical composition, and use thereof

Disclosed are a somatosensory remote controller, a somatosensory remote control flight system and method, and a remote control method. The somatosensory remote controller comprises: a motion sensor, a controller, a first transmission module, and a remote controller body. The motion sensor, the first transmission module, and the controller are all disposed on the remote controller body, and the motion sensor and the first transmission module are electrically connected to the controller. The motion sensor acquires initial state information of a current position of the remote controller body and movement information about movement of the remote controller body, and transmit the same to the controller. The controller is configured to receive, according to the initial state information and the movement information, a flight instruction, and send the flight instruction via the first transmission module.

Somatosensory remote controller, somatosensory remote control flight system and method, and head-less control method

A control system is disclosed. The control system comprises a controlling terminal and a controlled device; the controlling terminal comprises a height measuring device and a processing unit; the height measuring device is configured to measure and obtain a height information of the controlling terminal, and send the height information to the processing unit; the processing unit is configured to receive the height information and generate an operation command; the controlled device is configured to receive the operation command and perform a corresponding motion according to the operation command.

Control system and method for drone with remote controller

An iridinesulfonamide compound having isocitrate dehydrogenase 1 (IDH1) inhibitory activity, pharmaceutically acceptable salts, solvates or hydrates thereof, a pharmaceutical composition, as well as use of the compound or the pharmaceutically acceptable salts, solvates or hydrates thereof, and the pharmaceutical composition thereof in treating IDH1 mutation induced cancer. 

Iridinesulfonamide compound and use method thereof

Provided are a sultam compound having isocitrate dehydrogenase 1 (IDH1) inhibitory activity as represented by formula I or pharmaceutically-acceptable salts, solvates or hydrates thereof, a preparation method thereof, and a pharmaceutical composition containing the compound. The compound or the pharmaceutically-acceptable salts, solvates or hydrates thereof, and the pharmaceutical composition containing the compound can be used to treat IDH1 mutation-induced cancers. 

Sultam compound and application method thereof

The present application relates to a macrocycle containing aminopyrazole and pyrimidine, which is represented by formula (I), a pharmaceutical composition thereof, and a use thereof in inhibiting tropomyosin receptor kinase (Trk) activity and in treating diseases in mammals that are mediated by Trk. 

Macrocycle containing aminopyrazole and pyrimidine and pharmaceutical composition and use thereof

Provided is an amino pyrazolopyrimidine compound as represented by the following structural formula used as a neurotrophic factor tyrosine kinase receptor inhibitor. The compound can inhibit the activity of Trk kinase and can treat diseases mediated by a Trk tyrosine kinase receptor in mammals. 

Amino pyrazolopyrimidine compound used as neurotrophic factor tyrosine kinase receptor inhibitor

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Beijing, China

Yanqing Yang