Chinese Academy of Sciences

Beijing Baidu Netcom Science Technology Co., Ltd

Tianjin Genovo Biotechnology Co., Ltd.

Yanpeng Wang

Caixia Gao

Jin-Long Qiu

Chao Li

Shiyong Li

Mo Zhou

Bingqing Shao

Zhaogeng Li

Yidong Ran

Yuan Zong

Zhen Liang

Kang Zhang

Qiwei Shan

Qianna Song

Dou Shen

Fengti Qiu

Hu Xu

Zhigang Zeng

Zhenyuan Sun

Pengfei Yan

A method and apparatus for cross-computing power cluster communication, an electronic device, and a computer readable storage medium, are provided. An implementation of the method includes: in response to a communication initiator and a communication receiver respectively belonging to different computing power clusters, increasing a RDMA connection count on the basis of an initial connection count until a detected actual bandwidth value no longer increases, to obtain a target connection count; increasing, with the RDMA connection count being maintained at the target connection count, a Buffer size on the basis of an initial size until a detected actual bandwidth value no longer increases, to obtain a target size; determining cross-cluster transmission parameters, based on the target connection count and the target size; and communicating, cross-cluster transmission parameters, with the communication receiver belonging to a different computing power cluster.

Method and apparatus for cross-computing power cluster communication, electronic device and storage medium

The present invention provides a method for improving plant genetic transformation and gene editing efficiency. Specifically, the method improves the regeneration efficiency of plant genetic transformation and/or improves the efficiency of plant gene editing by expressing genes that promote plant cell division, especially meristematic cell division.

Method for improving plant genetic transformation and gene editing efficiency

A method of responding to an operation, an electronic device and a storage medium are provided, which relate to a field of cloud computing, and in particular to a field of cluster technology. The specific implementation solution includes: performing, in response to determining that a target operation performed by a target client on a shared resource has timed out, a fault detection on the target client to obtain a fault detection result; and implementing, in response to determining that the fault detection result represents that the target client has a fault, an update operation to obtain a target authority identifier, so that the target client is prevent from continuing to perform the target operation by using the target authority identifier.

Method of responding to operation, electronic device, and storage medium

The invention disclosed a method for conducting site-directed modification to a plant genome using non-inheritable materials. The method provided in the present invention specifically comprises the following steps: introducing a non-inheritable material into a cell or a tissue or a part of the plant of interest; wherein said non-inheritable material is a nuclease specific to said target fragment or an mRNA expressing said nuclease, thereby the target fragment is cleaved by said nuclease and site-directed modification to the target fragment is achieved through DNA repairing in the plant. By introducing a non-inheritable material of sequence-specific nuclease, site-directed mutation in a plant gene can be achieved, and no exogenous gene or nucleic acid fragments will be integrated into the plant as obtained. Therefore, the present invention can lead to more precise genome function study and higher biosafety in breeding.

Method for making site-directed modification to plant genomes by using non-inheritable materials

Provided relates to the field of genetic engineering. In particular, a method for base editing in plant is provided. More specifically, a highly efficient A to G base editing method for a target sequence in a genome of a plant (e.g., a crop plant) by a guide RNA-directed CRISPR-adenine deaminase fusion protein and the plant and their progeny produced by the method are provided.

Method for base editing in plants

In one aspect, this disclosure relates to a wheat plant, plant part or plant cell that has increased resistance to powdery mildew, wherein said plant comprises a loss of function mutation in the coding regions of two alleles selected from TaMLO-A1, TaMLO-B1 and TaMLO-D1 and reduced expression of the third TaMLO allele. In another aspect, this disclosure provides a method for producing a wheat plant, plant part or plant cell with increased resistance to powdery mildew, wherein the method comprises using targeted genome modification comprising introducing a loss of function mutation into the coding regions of two MLO alleles selected from TaMLO-A1, TaMLO-B1 and TaMLO-D1 and decreasing expression of the third TaMLO allele.

Wheat plants resistant to powdery mildew

The present invention provides a mutant wheat plant resistant to powdery mildew and producing method thereof, wherein the mutant wheat plant comprises a loss of function mutation in a TaMLO-A1, TaMLO-B1 and TaMLO-D1 nucleic acid sequence. The present invention also provides a method for determining the presence or absence of a mutant TaMLO-A1, TaMLO-B1 and TaMLO-D1 nucleic acid or polypeptide in a wheat plant.

Modified plants

Growing community of inventors

Beijing, China

Yanpeng Wang