Quantum Genomics

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

College De France

Yannick Marc

Fabrice Balavoine

Catherine Llorens-Cortes

Delphine Compere

Solène E Boitard

Ji Gao-Desliens

Mathilde Keck

Lionel Segard

The present invention relates to compounds, to compositions comprising the same, to methods for preparing the compounds, and the use of these compounds in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

Compounds and compositions comprising the same for treating hypertension or heart failure

The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.

Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same

The present invention relates to a pharmaceutical composition comprising, in at least one pharmaceutically acceptable support or vehicle, a combination of (3S,3S')4,4&#x2032;-disulfanediylbis(3-aminobutane 1-sulfonic acid) or a pharmaceutically acceptable salt or solvate thereof and a second active ingredient selected from the group consisting of angiotensin I converting enzyme inhibitors and angiotensin II receptor type I antagonists. Said composition is particularly useful for the treatment of hypertension and related diseases and conditions.

Combination of (3S,3S') 4,4&#x2032;-disulfanediylbis(3-aminobutane 1-sulfonic acid) and a second antihypertensive agent

Growing community of inventors

Saint Maur des Fosses, France

Yannick Marc