Sanofi-aventis

Sanofi

Synthelabo

Sanofi-synthelabo

Yannick Evanno

Laurent Dubois

Andre Malanda

David Machnik

Catherine Gille

Mireille Sevrin

André Malanda

Luc Even

Christian Maloizel

Nathalie Rakotoarisoa

Danielle De Peretti

Patrick Andre Lardenois

Pascal George

Jacques Froissant

Antonio Almario Garcia

Frank Marguet

Odette Legalloudec

Jonathan Reid Frost

Odile LeClerc

Gihad Dargazanli

Bernard M Raizon

Badia Ferzaz

Beno&icirc;t Marabout

Nathalie Rakotoarisoa-Rameix

Andrè Malanda

Laurent DuBois

J&eacute;sus Benavides

Phikip Janiak

R&eacute;gine Bartsch

Odile Leclerc

Dubois Laurent

The invention concerns compounds of general formula (I), wherein n, X, X, X, X, Y and W are as defined herein.  The invention also concerns a method for preparing said compounds and their therapeutic use.

N-(Heteroaryl)-1-heteroarylalky1-1H-indole-2-carboxamide derivatives, preparation and therapeutic use thereof

The invention relates to compounds of the general formula (I): Wherein X, Y, Z, Z, Z, Z, Zand n are as defined herein. The invention also relates to a method for making the same and to the use thereof in therapy.

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The disclosure relates to compounds of formula (I): wherein X, X, X, X, Y, n, A, and W are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

Bicyclic derivatives of azabicyclic carboxamides, preparation thereof and therapeutic use thereof

Compounds of formula (I): wherein R, R, R, R, Het and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

Polysubstituted derivatives of 6-heteroarylimidazo[1,2-a]pyridines, and preparation and therapeutic use thereof

The invention concerns compounds of general formula (I): Wherein n, X, X, X, X, Y, Z, Z, Z, Zand Zare as defined herein. The invention also concerns a process for the preparation of compounds of formula (I) and their therapeutic use.

N-(Aminoheteroaryl)-1H-indole-2-carboxamide derivatives, and preparation and therapeutic application thereof

Compounds of formula (I): wherein R, R, R, R, R, and X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

Polysubstituted 2-aryl-6-phenylimidazo[1,2-A]pyridine derivatives, and preparation and therapeutic use thereof

The invention relates to compounds of general formula (I): Wherein n, X, X, X, X, Y, Z, Z, Z, Z, Ra and Rb are as defined herein. The invention also relates to process for the preparation of compounds of formula (I) and their therapeutic use.

N-(aminoheteroaryl)-1H-indole-2-carboxamide derivatives, preparation thereof and therapeutic use therof

The invention relates to tricyclic N-heteroaryl-carboxamide derivatives having the formula (I): Wherein A, P, W, Z, Z, Z, Z, Z, Z, Z, Z, Rand R' are as described herein. The invention also relates to a method for preparing the same and to the therapeutic use thereof.

Tricyclic N-heteroaryl-carboxamide derivatives, preparation and therapeutic use thereof

This disclosure relates to compounds of formula (I): wherein G, G, G, G, n, Y, Z, Z, Z, Z, and Zare as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

Derivatives of indole-2-carboxamides and of azaindole-2-carboxamides substituted with a silanyl group, preparation thereof and therapeutic use thereof

This disclosure relates to compounds of formula (I): wherein X, X, X, X, n, Y, W, and A are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

N-azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof

The disclosure relates to compounds of formula (I): wherein X, X, X, X, Z, Z, Z, Z, Ra, Rb, n, Y, and W are as defined in the disclosure, or a salt thereof, or a hydrate or solvate thereof, and to processes for the preparation of these compounds and the therapeutic use thereof.

Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof

Compounds of formula (I): wherein R, R, R, R, Rand X are as defined in the disclosure, or an acid addition salt thereof, and the therapeutic use and process of synthesis thereof.

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Dannemois, France

Yannick Evanno