Cas Lamvac (guangzhou) Biomedical Technology Co., Ltd.

Cas Lamvac Biomedical Technology Co., Ltd.

Yanli Gu

Xiaoping Chen

Ting Jiang

Li Qin

Wen Hu

Yongchao Yao

Jiaojiao Li

Wenzhong Guo

Huihui Zhang

Shuozhou Huang

Yinbo Jiang

Zhu Tao

Provided are a chimeric antigen receptor and an application thereof; said chimeric antigen receptor contains a domain which identifies any one of, or a combination of at least two of, the malarial protein VAR2CSA, a protein tag on malarial protein VAR2CSA, or a compound capable of labeling the malarial protein VAR2CSA. The chimeric antigen receptor can identify the VAR2CSA protein or the recombinant protein (rVAR2) of any one of, or at least two of, the domains of the VAR2CSA protein which can bind to placental-like chondroitin sulfate A (pl-CSA). The VAR2CSA protein or rVAS2 protein is capable of targeting several different types of tumor cells by means of binding to the pl-CSA on the surface of the tumor cell.

Chimeric antigen receptor and application thereof

Growing community of inventors

Guangdong, China

Yanli Gu