Yonsei University

Ewha University-Industry Collaboration Foundation

Yangsoo Jang

Sung-Jin Hong

Dong Hoon Choi

Sejin Jeon

Myeong-Ki Hong

Hye-Young Yun

Tae Kyeong Kim

Goo Taeg Oh

The present invention pertains to: a marker composition for diagnosing atherosclerosis severity; a composition for diagnosing atherosclerosis severity; an atherosclerosis severity diagnosis kit including the composition; a method for screening substances for preventing or treating atherosclerosis; and a method for providing information about a diagnosis of atherosclerosis severity, wherein LGI3 expression or activity levels are used. According to the present invention, the severity of atherosclerosis can be diagnosed or predicted, and personalized medicine and predictive medicine can be practiced using such information. Moreover, the present invention can treat atherosclerosis without affecting other metabolic phenotypes by administering an LGI3 antagonist.

Marker for diagnosing atherosclerosis severity, and diagnostic method using same

The present invention relates to a stent for protecting a branch blood vessel at a branch-point lesion. The stent is inserted into and widened in a main blood vessel having the branch blood vessel extending in a slant from the branch-point lesion, thereby simultaneously expanding the main blood vessel and providing a smooth flow of blood towards the branch blood vessel. As a result, it is possible to simultaneously expand the main blood vessel and to sufficiently secure a passage from the main blood vessel towards the branch blood vessel. As such, the flow of blood is kept smooth. Further, after the stent is inserted into the main blood vessel, another stent, a guide wire, and related tools and catheter can be inserted in the direction of the branch blood vessel in a more accurate manner.

Stent for protecting bifurcated blood vessels in bifurcation lesion

Growing community of inventors

Seoul, South Korea

Yangsoo Jang