Postech Academy-industry Foundation

Yanggy Lee

Jihoon Kim

Dong Keun Han

Won Jong Kim

Kwideok Park

A donor capable of controlled release of nitric monoxide and a prosthetic implant whose surface is coated with this donor are disclosed. The donor comprises a main chain of an organic polymer and a side chain that is covalently linked to the main chain and has a diazeniumdiolate functional group. The donor for controlled release of nitric monoxide exists in a fluid state such as liquid at room temperature and undergoes a sol-to-gel phase transition at a physiological pH as the temperature increases above the critical temperature. The critical temperature of the phase transition is in the range of 25 to 35&#xb0; C., and the gel is a hydrogel without chemical cross-links.

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Gyeongsangnam-do, South Korea

Yanggy Lee