The Procter Gamble Company

City of Hope

Beijing Didi Infinity Technology and Development Co., Ltd.

China Tobacco Yunnan Industrial Co., Ltd

Yang Su

Ross Strand

Yunming Shi

Guannan Wang

Thanigaivel Shanmugam

Xiaoxiao Li

Xiaowei Li

David A Horne

Yongkuan Chen

Ping Lei

Shanzhai Shang

Jingmei Han

Zhiqiang Li

Chengya Wang

Hongmei Yang

Dalin Yuan

Ru Wang

Xu Zeng

Jianguo Tang

Xudong Zheng

Yuelong Ma

Xiaoli Xu

Yuan Chen

Liu Hong

Yifan Wang

Yi-Jia Li

Weimin Gong

Yunhua Qin

Dong Xiao

Chao Li

Deshou Mao

Lingxuan Liu

Angela L Perkins-Harki

Duoqing Fan

Hui Wang

Jie Tang

Yiqin Wu

Wei Liu

Xinrui Li

He Gu

Haibin Gao

Yuanchun Dou

Jun Wu

Wen Yang

Jinghui Cheng

Xiaolong Ma

Lu Wang

Wenjun Gao

Leave-on oral care compositions including a hyaluronic acid or a salt thereof good spreadability and improved retention period are provided for promoting Gum Health of a user. Kits and methods are also provided.

Leave-on oral care compositions

Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Leave-on oral care compositions can comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer, and an additional polymer.

Leave-on oral care compositions comprising a hyaluronic acid or a salt thereof having good spreadability and improved retention period are provided for promoting Gum Health of a user.

Leave-on oral care compositions comprising a hyaluronic acid, and a gum-strengthening polyol are provided for promoting Gum Health of a user.

Leave-on oral care compositions having good spreadability and improved retention property are provided for promoting Gum Health of a user. Said leave-on oral care compositions comprise a hyaluronic acid or a salt thereof, a polyacrylic acid as a mucoadhesive polymer and an additional polymer.

A modular multifunctional electronic smoking paraphernalia includes a main body module provided with a slide rod a and a slide rod b, a cigarette holder module provided with a slide groove a, and an atomization module provided with a slide groove b. The cigarette holder module is detachably and slidably connected to the main body module by the slide rod a and the slide groove a. The atomization module is detachably and slidably connected to the main body module by the slide rod b and the slide groove b. In the present invention, the smoking paraphernalia is designed as three detachable modules, namely, the main body module, the cigarette holder module and the atomization module, which is convenient for the smoker to operate.

Modular multifunctional electronic smoking paraphernalia

Systems and methods for presenting a prompting message on a user interface of an online to offline service application in a user terminal are provided. A method includes: obtaining, from a user terminal, a service request for a first service type, wherein the service request includes a location of the user terminal; determining a first supply-demand ratio of the first service type based on the location of the user terminal; determining whether the first supply-demand ratio is greater than a first ratio threshold; and in response to determining that the first supply-demand ratio is not greater than the first ratio threshold, sending, to the user terminal, a first bubble prompting message presented on a user interface of the user terminal, wherein the first bubble prompting message includes a second service type and a response time of the second service type.

Artificial intelligent systems and methods for presenting a prompting message on a mobile device

Oral care compositions comprising citrulline and stannous ion source with a specific pH range are provided for promoting Gum Health of a user.

Oral care compositions for promoting gum health

The present invention provides an oral composition comprising: (a) from 1 wt % to 60 wt % of a calcium-containing abrasive; (b) a calcium-catching phosphate source in an amount sufficient to provide at least 100 mM of phosphate ions, PO; (c) no more than 20 wt % of a humectant; and (d) at least 5 wt % of water; wherein the oral composition has a pH from 8 to 11.

Anti-calculus oral compositions

A composition used to develop a reagent for investigating Ubl-modifications in cellular functions and in the treatment of cancer is provided. The composition comprises gold nanoparticle (AuNP)-ligand conjugates that include at least two components: gold nanoparticles (AuNPs) and modified ubiquitin- or ubiquitin-like interacting motif (UIM or ULIM) mimetics. In one embodiment, the modified ULM mimetic is a modified SUMO interaction motif (SIM) mimetic. According to the embodiments described herein, the compound inhibits ubiquitin- or ubiquitin-like protein (Ubl)-mediated protein-protein interactions and sensitizes cells to ionizing radiation. The modified UIM and ULIM mimetics may be conjugated to the AuNP such that each AuNP is conjugated to a plurality of modified UIM or ULIM mimetics. The modified ULIM mimetics may be conjugated to the AuNP via a thiol group.

Multi-valent poly-Ubl chain inhibitors and methods of use

Growing community of inventors

Beijing, China

Yang Su