Wuhan University

Hubei University

Yangtze Memory Technologies Co., Ltd.

Wuhan Yzy Biopharma Co., Ltd.

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Huawei Device Co., Ltd.

Huawei Digital Power Technologies Co., Ltd.

Valeo Vision

Huazhong University of Science and Technology

Yang Liu

Lixin Ma

Tao Wang

Fei Wang

Pengfei Zhou

Wu Liu

Mengyong Liu

Guoliang Chen

Liu Hu

Lijuan Fang

Yu Zhang

Lei Zhang

Wei Yang

Jing Li

Wei Shui

Feng Ding

Dinglong Pan

Bin Hu

Palma Rocchi

Hui Luo

Tao Huang

Pingwu Yang

Juan Iovanna

Wanping Chen

Haiqing Zhou

Lei Fan

Ling Peng

Kai Cui

Daiwei Bi

Yaping Wang

Qi Liu

Huimin Gao

Yuhao He

Zhengzheng Guo

Xin Fang

Zijie Ren

Xiaoman Jiang

Cancan Yi

Han Xiao

Wenqiang Li

Mi Huang

Kesuo Fan

Yi Xia

Fanqi Qu

Jinqiao Wan

Menghua Wang

Xiangyu Shi

Jianhui Liu

Yinquan Huo

Yuanqi Cai

Aneng Cui

Qinghong Fang

Xin Zhu

Yalan Jia

Ruyi He

Xiaoai Xue

Haichun Li

Disclosed is a sodium petroleum sulfonate collector for fluorite flotation, comprising sodium petroleum sulfonate and non-polar oil, wherein the molar ratio of the non-polar oil to the sodium petroleum sulfonate is 3.33-5.67, the sodium petroleum sulfonate comprises raw material oil and active substance, the molecular weight of the raw material oil is 350-450, the molecular weight of the sodium petroleum sulfonate is 500-750, the aromatic hydrocarbon comprises benzene ring hydrocarbon and naphthalene ring hydrocarbon, the content of the benzene ring hydrocarbon is 5% to 11%, and the content of the naphthalene ring hydrocarbon is 5% to 5.2%, the raw material oil needs to be sulfonated by sulfur trioxide, and the molar ratio of the aromatic hydrocarbon to the sulfur trioxide in the raw material oil is 2.4 to 5. The sodium petroleum sulfonate collector proposed by this disclosure is both efficient and low temperature resistant.

Sodium petroleum sulfonate collector for fluorite flotation and its preparation and application method

An apparatus for wafer bonding includes a first bearing table configured to hold a first wafer provided with at least one first alignment mark; a second bearing table, opposite to the first bearing table, and configured to hold a second wafer provided with at least one second alignment mark; an alignment component, located on at least a side of the first or second bearing table, and configured to determine first and second position parameters of the first and second alignment marks, respectively, by using an optical beam; a mobile component, connected to the first and second bearing tables, and configured to adjust, according to the first an second position parameters, a relative position between the first and second wafers until a relative position between the first and second alignment marks satisfies a predetermined bonding condition; and a bonding component, connected to the first and second bearing tables, and configured to bond the first wafer to the second wafer.

Wafer bonding apparatus and method

Argonaute proteins from prokaryotes (pAgos) and applications thereof are provided, the pAgo is from a mesophilic prokaryote ofand named as KmAgo, the pAgos and applications thereof are capable of site-specific modification of intracellular and extracellular genetic material, and thus can be effectively applied to many fields of biotechnology, such as nucleic acid detection, gene editing and gene modification, and provide a new tool for gene editing, modification and molecular detection of the pAgo polypeptides.

Argonaute proteins from prokaryotes and applications thereof

A machine vision-based crystallizer nozzle centering method includes: S, performing image acquisition on a tundish car lower nozzle and a crystallizer nozzle; S, performing an edge enhancement using guide image filtering; S, performing an edge extraction on a first image set using an ant algorithm, and obtaining a second image set; S, performing smoothing processing and a centerline extraction on the second image set using a morphological closing operation respectively, and obtaining a centerline equation; S, centering the crystallizer nozzle in a width direction according to the centerline equation, and obtaining a width centering result; S, installing two second image acquisition apparatuses symmetrically on a center extension line of the crystallizer nozzle, and obtaining a thickness centering result using the second image acquisition apparatuses; and S, adjusting a position of a tundish car according to the width centering result and the thickness centering result.

Machine vision-based crystallizer nozzle centering method and system

An interface circuit, a string, and a system that are applied to power line communication, to lower device specifications, includes: an inverter, an optimizer group, a capacitor, a magnetic ring, power lines, and a signal line. An optimizer in the optimizer group is configured to adjust a size of a direct current output by a photovoltaic module connected to the optimizer. Two ends of the signal line passing through the magnetic ring are connected to the inverter. Two ends of a power line passing through the magnetic ring are respectively connected to the capacitor and the optimizer group. By using the foregoing interface circuit, a high voltage of a direct current output by the optimizer group is prevented from being introduced into the inverter, thereby reducing a specification requirement of a device such as a capacitor.

Interface circuit, string, and system applied to power line communication

An application of a prokaryotic Argonaute protein with only a cleavage activity of a target ribonucleic acid (RNA) in RNA editing is provided. The Argonaute protein is derived from a mesophilic prokaryotes, and its amino acid sequence is shown in SEQ ID NO: 1 or a protein with high similarity to SEQ ID NO: 1 and the same function. This protein has binding activity to a single-stranded guide DNA and nuclease activity only to the target RNA complementarily paired with the single-stranded guide DNA. Therefore, the protein can be utilized for in vitro and in vivo targeted RNA editing, providing a new powerful tool for RNA editing.

Application of prokaryotic Argonaute protein with only RNA target cleavage activity in RNA editing

A method and apparatus for wafer bonding. The method includes that, a first position parameter of a first alignment mark on a first wafer is determined by using a optical beam; a second position parameter of a second alignment mark on a second wafer is determined with the optical beam, the optical beam has a property of transmitting through a wafer; a relative position between the first wafer and the second wafer is adjusted with the optical beam according to the first position parameter and the second position parameter until the relative position between the first alignment mark and the second alignment mark satisfies a predetermined bonding condition; and the first wafer is bonded to the second wafer.

Mbp_Argonaute proteins from prokaryotes and application thereof are provided. The Mbp_Argonaute protein consists of an amino acid sequence as shown in SEQ ID NO: 1 or a sequence with at least 50% or at least 80% of homology with the amino acid sequence as shown in SEQ ID NO: 1. An Argonaute protein gene derived from a cold-resistant prokaryoteis synthesized and named as MbpAgo, which has binding activity to single-stranded guide DNA and has nuclease activity to target RNA and/or target DNA complementarily paired with the single-stranded guide DNA, the MbpAgo can be used for the target RNA editing in vivo and in vitro to achieve site-specific modification of genetic material. The MbpAgo can modify highly-structured RNAs and not affect an endogenous RNAi pathway of animal and plant cells, provides a new and powerful tool for RNA editing with high cleavage activity and good specificity.

Mbp_Argonaute proteins from prokaryotes and applications thereof

The disclosure provides a method for determining a slope slip plane with a gently-inclined soft interlayer, including: S1, determining a curve formed with a slip arc of a trailing edge tearing plane, a soft interlayer plane and a slip arc of a leading edge shear opening as a slope slip plane; S2, calculating a slip plane stability coefficient; S3, determination of a position of the gently-inclined soft interlayer plane: if the slip plane stability coefficient is less than 1 but close to 1, determining that the position of the slope slip plane is accurate; otherwise, moving the position of the soft interlayer plane and repeating steps S1 and S2, until the slip plane stability coefficient is less than 1 and close to 1. The method is simple, and has a high accuracy for determining a non-circular slip plane with a soft interlayer as a bottom slip plane.

Method for determining slope slip plane with gently-inclined soft interlayer

An active resonance C-type buoyant flap wave energy converter includes a rigid frame, a flap, a mass center adjustment assembly and a power generation assembly. The rigid frame is connected to a marine facility, and includes a main body and a support shaft provided at a bottom thereof. The flap is swingingly arranged on the support shaft. The flap is located under water surface, and swings back and forth around the support shaft under an action of a wave. The mass center adjustment assembly is configured to adjust a mass center of the flap to make a natural period of the flap same as a wave period, so as to achieve a resonance between the flap and the wave. The power generation assembly is arranged on the support shaft and is located in the flap.

Active resonance C-type buoyant flap wave energy converter

Provided are compositions comprising a MSBODY and a cytotoxic immune cell (e.g., Cytokine-induced killer cell) to form Armed Activated CIK cells (ACCs), wherein the MSBODY comprising a first antigen binding moiety that has specificity for a tumor antigen, and a second antigen binding moiety that binds to the cell. Provided are also methods preparing a composition comprising a MSBODY and a cytotoxic immune cell, and methods for treating patients with CIK cells armed with bispecific antibodies.

Bispecific antibody-mediated cancer therapy with cytokine-induced killer cell

Electric drive unit

The present invention provides a bispecific antibody. The bispecific antibody provided by the present invention comprises a single-chain unit and a monovalent unit, wherein the single-chain unit has a specific binding capability against surface antigen CD3 of an immune cell; the monovalent unit has a specific binding capability against the surface antigen EpCAM of a tumor cell; the single-chain unit comprises a single-chain variable fragment ScFv fused with an Fc fragment; and the monovalent unit comprises a light chain and heavy chain pair. The present invention also provides a preparation method of the bispecific antibody and pharmaceutical use of these antibodies.

Construction and application of bispecific antibody EpCAM&#xd7;CD3

Wireless router

The present invention relates to novel compounds of formula (A):  The invention also relates to process of preparation of compounds of formula (A), to composition comprising them and to their application in therapeutics and in particular in cancers.

Triazole derivatives, their preparation and their application in therapeutics

Growing community of inventors

Wuhan, China

Yang Liu