Huazhong University of Science and Technology

Yang Jin

Zheng Wang

Ming Ma

ZhiHui Wang

Shi Chen

Qi Tan

JianCai Wu

WenJuan Chen

QingSong Wu

Can Xiang

JingJing Deng

YingCong Zhang

Fei Luo

A preparation method of a tumor microparticle encapsulating a metabolic inhibitor includes following steps. A tumor cell is cultivated, and a statin drug is added to a culture medium after the tumor cell grows stably. Then, the tumor cell is irradiated with an ultraviolet, and then the tumor cell is incubated in a cell incubator for 22˜26 hours. After the incubation, cell supernatant is collected and the tumor microparticle encapsulating the metabolic inhibitor is obtained through a gradient centrifugation. The preparation method uses tumor cell-derived microparticles as drug delivery platforms, with a simple preparation process that preserves functions such as biosafety, biocompatibility, targeting, and intercellular communication. The preparation method discovers new uses of a statin drug, which can inhibit tumor growths with the statin drug, regulate tumors metabolism and improve a tumor microenvironment, and have a potential to enhance a chemotherapy efficacy and delay a chemotherapy resistance.

Preparation method and application of tumor microparticles encapsulating metabolic inhibitors

A hospital human resource information management file cabinet is provided, including a support base plate, a lower surface of which is fixedly connected to upper surfaces of three fan assemblies; left ends of the three fan assemblies are respectively connected to outer surfaces of three first conduits, and front ends of the three first conduits are in communication with back ends of three second conduits. The file cabinet speeds up air flow rate on surfaces of the files therein, prevents moisture causing damage to the files, reduces information loss, and continuously treats the moisture inside, which in turn guarantees the service life of the file cabinet.

Hospital human resource information management file cabinet

Growing community of inventors

Wuhan, China

Yang Jin