Hangzhou Singclean Medical Products Co., Ltd

Yang Fu

Jie Li

Wei Huang

Jue Wang

Lingling Lyu

Zhongyi Chen

A cyclical and continuous device and method for wet sieving of polysaccharide granules are provided. The device includes a first dosing tank, a second dosing tank connected to the first dosing tank by a first circulation pump, a first suction filtration tank connected to the second dosing tank by a second circulation pump, and a second suction filtration tank connected to the first dosing tank by a third circulation pump. An overflow port provided on a side wall of the second dosing tank is higher than a feed port of the first dosing tank. A sieve of a mesh filter for coarse powder is disposed in the first dosing tank. A sieve of a mesh filter for fine powder is disposed in the second dosing tank. A stirring device is disposed in both the first dosing tank and the second dosing tank.

Cyclical and continuous device and method for wet sieving of polysaccharide granules

The present invention provides a method for removing an organic solvent from starch hemostatic microspheres, comprising the following steps: 1. taking to-be-dried starch hemostatic microspheres and laying them flatly on drying trays with attention to laying them as uniformly and thinly as possible; 2. taking an adsorbent and subpackaging it into dialyzing paper bags for sealing; and 3. placing the trays and the dialyzing paper bags completed in the previous two steps on separators of a low-temperature vacuum oven in layers, setting the oven temperature at 0-20° C., then vacuumizing and keeping pressure for 15-48 hours. The method provided by the present invention can reduce organic solvent residue in the starch hemostatic microspheres to less than 0.05%, which meets the requirements of relevant standards for medical devices, thereby improving safety of products.

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Zhejiang, China

Yang Fu