Tsinghua University

Yang-Bao Miao

Hsing-Wen Sung

Kuan-Hung Chen

Wen-Yu Pan

Po-Ming Chen

Po-Kai Luo

A spiky metal organic framework is provided in the present disclosure. The spiky metal organic framework is formed by a coordination reaction between at least one metal ion and an organic ligand, and includes a body and a plurality of spike-like structures. The body is a spherical shape, and a particle size of the body is 1 &#x3bc;m to 3 &#x3bc;m. The spike-like structures are distributed on a surface of the body, a diameter of each spike-like structure is 15 nm to 35 nm, and a length of each spike-like structure is 250 nm to 400 nm.

Spiky metal organic framework, method for fabricating thereof, and kit for treating cancer

The present disclosure provides an oral drug composition including a prodrug and a carrier. The prodrug bonds an active drug to a spacer with a covalent bond, in which the spacer has a disulfide bond. The carrier is for carrying the prodrug with an efficient amount, and the carrier includes a &#x3b2;-1,3-D-glucan.

Growing community of inventors

Hsinchu, Taiwan

Yang-Bao Miao