Shenyang Pharmaceutical University

Yanfeng Liu

Chunfu Wu

Jinghai Zhang

Zhou Yang

Jianhai Zhang

Yong Cui

Runlin Ma

Siling Wang

The present application relates to inhibitors of VGSC&#x3b2;3 protein and use thereof and methods of using the VGSC&#x3b2;3 protein or an inhibitor thereof to diagnose, prevent and treat cancer, and to screen antineoplastic agents using the VGSC&#x3b2;3 Protein or its regulatory sequences.

Target of VGSC &#x3b2;3 protein for prevention, treatment and diagnostic detection of cancers

The present invention provides an active peptide purified from scorpions, and derivatives, analogs and active fragment which are produced by using genetic engineering technology. The analgesic active peptide VGG is extracted, separated and purified from scorpion, and its amino acid sequence is shown as below: The present invention further provides a use of the peptides in preparation of an analgesic drug, where the peptide is mixed with a pharmaceutically acceptable carrier to prepare into forms for injection, oral administration, transdermal absorption, and transmucosal absorption.

Analgesic active peptide VGG, preparation and use thereof

The present invention relates to a peptide having analgesic and antitumor activity derived from the scorpion and partial fragment, derivative or analogue thereof having analgesic and antitumor activity, and preparation method and use thereof. The peptide having analgesic and antitumor activity is obtained by extraction, isolation and purification from the scorpion or scorpion venom. The peptide having analgesic and antitumor activity derived from the scorpion and partial fragment, derivative or analogue thereof can be obtained by chemical synthesis method or bioengineering method. The peptide having analgesic and antitumor activity derived from the scorpion and partial fragment, derivative or analogue thereof is used as the analgesic and antitumor drugs.

Method of using a peptide having analgesic and antitumor activity from scorpion

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Shenyang, China

Yanfeng Liu