Temasek Life Sciences Laboratory Limited

Yanbin Liu

Lianghui Ji

Chong Mei John Koh

Chong Mei Koh

Sihui Amy Yap

Si Te Ngoh

The present invention relates to the field of molecular biology and more particularly to promoters useful for metabolic engineering in yeast or fungi for the production of biobased chemicals with broad applications. Intron-containing promoters with strong activity during oil-accumulation stages are particularly useful for genetic engineering in yeast and fungi, particularlyorgenera. Such promoter are capable of driving strong expression of RNA or proteins in species of theorgenera.

Intron-containing promoters and uses thereof

The present invention relates to the field of fungal production fatty alcohols. More specifically, the present invention relates to genetically modified host cells, nucleic acid constructs and culture medium for the production of fatty alcohols in

Production of fatty alcohols in Rhodosporidium

The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of carotenoids in fungal hosts selected fromandgenera.

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The present invention relates to the field of fungal biotechnology, more particularly to a strong inducible gene expression system in fungal species, such as a species of thegenus or thegenus.

The present invention relates to the field of fungal biotechnology, more particularly to genetic engineering methods for the production of polyunsaturated fatty acids (PUFA) in fungal hosts selected fromandgenera. The present invention further relates to a modified fungal host cell having reduced native aldehyde dehydrogenase (ALD 1) enzyme activity, and methods for producing omega-3 and omega-6 fatty acids and triacylglycerides, by growing said fungal host cell under suitable conditions.

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Singapore, Singapore

Yanbin Liu