Colgate Palmolive Company

Yanan Hu

Harsh Mahendra Trivedi

Laurence Du-Thumm

Tao Xu

Richard J Sullivan

Ying Yang

Zhiqiang Liu

Lyndsay Schaeffer-Korbylo

Stacey Lavender

Davide Miksa

Ralph Peter Santarpia, Iii

Cortney L Worrell

Chanda Macias

Richard Scott Sullivan

Ralph Peter Santarpia Iii

Zhiqiang Lui

Laurence Du Thumm

The present invention discloses novel uses of specific menthol-derivative compounds of Formula 1, and compositions thereof, for methods of providing oral and systemic health care benefits, and methods of up-regulating or down-regulating periodontal disease metabolites: Formula 1 wherein, X is an oxygen atom or an NH radical; and R is an unsubstituted or substituted aryl or aliphatic radical. In some embodiments, the oral and systemic health care benefits include biofilm anti-attachment, anti-inflammation, anti-oxidant, anti-bone loss, and anti-microbial benefits. In some embodiments, the periodontal disease metabolites correspond to healthy and/or diseased oral status and allow differential diagnosis of oral health. 

Menthol-derivative compounds and use thereof as oral and systemic active agents

This, intention relates to methods of assessing the bioflora of the mouth and of providing appropriate treatment utilizing a basic amino acid in accordance with the assessment.

Oral care methods and systems

Growing community of inventors

San Jose, CA, United States of America

Yanan Hu