Ben-gurion University of the Negev Research and Development Authority

B.g. Negev Technologies and Applications Ltd.

Yana Yudilevich

Joseph Kost

Tamar Traitel

Moshe Elkabets

Aharon Azaguri

Eden Bergman

Aharon (Roni) Azagury

Rivka Goldbart

Itay Rousso

Provided herein methods for treating a subject suffering from a disease or a disorder associated with hyperproliferating cells, by irradiating the cells with low-frequency ultrasound at an intensity that is either below the cavitational threshold intensity for the ultrasound frequency, or is characterized by a low-frequency mechanical index below 2.5. The methods may further comprise determining an elasticity value of the cells, and adjusting the ultrasound intensity accordingly.

Low intensity ultrasound therapy

Methods of treating a subject suffering from a disease or a disorder associated with hyperproliferating cells. The method includes non-invasively administering to the subject ultrasound at a low intensity in a dose effective to selectively prevent the growth of the hyperproliferating cells or to eliminate the hyperproliferating cells in the subject, while substantially not affecting the cell viability of normal cells of the subject. The low intensity is pre-determined to be lower than a cavitational threshold intensity for a selected frequency.

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Beer Sheva, Israel

Yana Yudilevich