Zynga Inc.

Silver Creek Pharmaceuticals, Inc.

Yan Zhang

Daniel McCaffrey

Kevin A Lee

Kenneth Rudin

Ananda Ghosh

Matthew D Onsum

Laura D J Antipov

Shawdee Eshghi

Kristopher M Kuchenbecker

Bjorn L Millard

Andrea D Nickerson

Timothy R Stowe

Cadir Lee

Laura DJ Antipov

Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue.

Method of treating skin tissue damage by topically administering a bi-specific protein comprising a human insulin-like growth factor variant and a human annexin A5 variant

Bi-specific therapeutic proteins, in vivo methods of use thereof and encoding nucleic acids thereof

Method of inhibiting apoptosis or promoting cell survival by providing a bi-specific protein comprising insulin-like growth factor IGF-1 and Annexin A5

An optimized friend recommendation system is described. An active social network (ASN) of a player of an online game is determined based on a frequency of reciprocated communications between the player and friends of the player. The ASN of the player has friends of the player with a minimum number of closed-loop communications with the player within a predetermined duration. The social network of non-ASN friends outside the ASN of the player is identified. One or more non-ASN friends identified and suggested to socially engage with the player in an online game based on the social network of non-ASN friends of the player outside the ASN of the player are.

Friend recommendation system

Method of protecting tissue from damage by administering a bi-specific therapeutic protein comprising insulin-like growth factor 1 (IGF-1) and Annexin A5

Bi-specific annexin A5/IGF-1 proteins and methods of use thereof to promote regeneration and survival of tissue

Social network information of a player of a computer-implemented game is accessed to analyze a social interaction of the player with other players from the social network information to recommend other players of the social network of the player to further communicate with. A recommendation of other players is generated to the player based on a frequency of the social interaction. A selection of players from the recommendation is received from the player. A communication message is generated to the selected players.

Friend recommendation system for a computer-implemented game

Social network information of a player of a computer-implemented game is accessed to identify active players from the social network information. The active players each have a minimum number of reciprocated communications with the player within a time range. A recommendation of players is generated to the player based on the identified active players.

Friend recommendation system based on an active social network

Social network information of a player of a computer-implemented game is accessed to identify non-active players from the social network information. The non-active players each have a minimum number of unreciprocated communications with the player within a time duration. A recommendation of the recommended players is generated to the player based on the non-active players.

Friend recommendation system based on a non-active social network

A system and computer-implemented method for cross-promoting electronic games is provided. First and second electronic game databases are configured to store first and second game user attributes relating to first and second electronic game, respectively. An aggregator database is coupled to the first and second electronic game databases and is configured to store a first game user attribute, associated with the user and relating to a first electronic game, and user data of a user of the first electronic game. A processor is coupled to the aggregator database and configured to automatically associate a second game user attribute to the user according to a predetermined rule based on at least one of the first game user attribute stored in the aggregator database and the user data. The second game user attribute associated to the user by the processor is stored in the aggregator database.

Rules-based engine for cross-promotion platform

A system and computer-implemented method for promoting an electronic game of a plurality of electronic games is provided. A storage module may store a user attribute relating to a first electronic game. An aggregator module is configured to aggregate a user attribute from each of a plurality of electronic games including the first electronic game. A transmitter module may transmit the user attribute relating to the first electronic game to the aggregator module upon the user attribute being stored in the storage module. An association module may associate, using an application programming interface, a user attribute of a second electronic game of the plurality of electronic games different from the first electronic game, the association module associating based on a rule engine implemented by the API and at least one of the user attribute of the first electronic game and game data of the second electronic game.

Real-time data services API

A system and computer-implemented method for promoting an electronic game of electronic games is provided. A user interface module is configured to receive an input from a user relating to playing a first and second electronic game. A processor-implemented association engine, operatively coupled to the user interface, is configured to associate user attributes of the first and second electronic games to the user based on the input. An application programming interface (API) is configured to associate a user attribute of a third electronic game different from the first and second electronic games, the API configured to associate based, at least in part, on rule engine implemented by the API and at least one of the user attributes of the first and second electronic games and game data of the third electronic game.

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Foster City, CA, United States of America

Yan Zhang